Literature DB >> 30250900

CHMP4C: A novel regulator of the mitotic spindle checkpoint.

Eleni Petsalaki1, George Zachos1.   

Abstract

The mitotic spindle checkpoint delays anaphase onset until all chromosomes have achieved stable kinetochore-microtubule attachments. Here, we discuss recent findings showing that CHMP4C, a component of the endosomal sorting complex required for transport (ESCRT) machinery, protects human cells against chromosome missegregation by promoting localisation of the ROD-ZW10-ZWILCH (RZZ) spindle checkpoint complex to unattached kinetochores.

Entities:  

Keywords:  Biology of malignant cells; CHMP4C; ESCRT; RZZ; ZW10; mitosis; spindle checkpoint

Year:  2018        PMID： 30250900      PMCID： PMC6149907          DOI： 10.1080/23723556.2018.1445944

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

Review 1.  The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.

Authors:  Andrea Musacchio
Journal:  Curr Biol       Date:  2015-10-19       Impact factor: 10.834

Review 2.  Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint.

Authors:  Sabine Elowe
Journal:  Mol Cell Biol       Date:  2011-05-31       Impact factor: 4.272

Review 3.  The Abscission Checkpoint: Making It to the Final Cut.

Authors:  Viola Nähse; Liliane Christ; Harald Stenmark; Coen Campsteijn
Journal:  Trends Cell Biol       Date:  2016-10-31       Impact factor: 20.808

Review 4.  Novel ESCRT functions in cell biology: spiraling out of control?

Authors:  Coen Campsteijn; Marina Vietri; Harald Stenmark
Journal:  Curr Opin Cell Biol       Date:  2016-03-28       Impact factor: 8.382

5.  Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling.

Authors:  Hongmei Wang; Xiaoyu Hu; Xia Ding; Zhen Dou; Zhihong Yang; Andrew W Shaw; Maikun Teng; Don W Cleveland; Michael L Goldberg; Liwen Niu; Xuebiao Yao
Journal:  J Biol Chem       Date:  2004-10-13       Impact factor: 5.157

6.  KNL1-Bubs and RZZ Provide Two Separable Pathways for Checkpoint Activation at Human Kinetochores.

Authors:  Virginia Silió; Andrew D McAinsh; Jonathan B Millar
Journal:  Dev Cell       Date:  2015-12-07       Impact factor: 12.270

7.  Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores.

Authors:  James M Kasuboski; Jason R Bader; Patricia S Vaughan; Sinji B F Tauhata; Michael Winding; Meghan A Morrissey; Michelle V Joyce; William Boggess; Larissa Vos; Gordon K Chan; Edward H Hinchcliffe; Kevin T Vaughan
Journal:  Mol Biol Cell       Date:  2011-07-20       Impact factor: 4.138

8.  Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.

Authors:  Gang Zhang; Tiziana Lischetti; Daniel G Hayward; Jakob Nilsson
Journal:  Nat Commun       Date:  2015-06-02       Impact factor: 14.919

9.  The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling.

Authors:  Eleni Petsalaki; Maria Dandoulaki; George Zachos
Journal:  J Cell Biol       Date:  2018-01-23       Impact factor: 10.539

10.  The RZZ complex requires the N-terminus of KNL1 to mediate optimal Mad1 kinetochore localization in human cells.

Authors:  Gina V Caldas; Tina R Lynch; Ryan Anderson; Sana Afreen; Dileep Varma; Jennifer G DeLuca
Journal:  Open Biol       Date:  2015-11       Impact factor: 6.411
  10 in total
  4 in total

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Authors:  Zhongbo Xu; Wenyan Yu; Lin Li; Guojuan Wang
Journal:  Medicine (Baltimore)       Date:  2022-10-14       Impact factor: 1.817

2.  Chromatin modified protein 4C (CHMP4C) facilitates the malignant development of cervical cancer cells.

Authors:  Shu-Li Lin; Mei Wang; Qing-Qing Cao; Qing Li
Journal:  FEBS Open Bio       Date:  2020-05-30       Impact factor: 2.693

3.  CHMP4C regulates lung squamous carcinogenesis and progression through cell cycle pathway.

Authors:  Bo Liu; Sixuan Guo; Geng-Hui Li; Yue Liu; Xu-Zhi Liu; Jian-Bo Yue; Hong-Yan Guo
Journal:  J Thorac Dis       Date:  2021-08       Impact factor: 2.895

4.  Using Drosophila melanogaster to Analyse the Human Paralogs of the ESCRT-III Core Component Shrub/CHMP4/Snf7 and Its Interactions with Members of the LGD/CC2D1 Family.

Authors:  Miriam Baeumers; Katharina Schulz; Thomas Klein
Journal:  Int J Mol Sci       Date:  2022-07-06       Impact factor: 6.208
  4 in total

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