Literature DB >> 30250887

ARF-NRF2: A new checkpoint for oxidative stress responses?

Delin Chen1, Omid Tavana1, Wei Gu1.   

Abstract

NRF2 (nuclear factor erythroid 2-related factor 2) is a transcription factor which plays a major role in oxidative stress responses by regulating antioxidant gene expression. We have recently identified the ARF tumor suppressor as a key regulator of NRF2. ARF can significantly inhibit NRF2 transcriptional activities, and the ARF-NRF2 interaction may function as a novel checkpoint for oxidative stress responses.

Entities:  

Keywords:  ARF; NRF2; Tumor suppressor; oxidative stress

Year:  2018        PMID： 30250887      PMCID： PMC6149754          DOI： 10.1080/23723556.2018.1432256

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

Review 1.  Divorcing ARF and p53: an unsettled case.

Authors:  Charles J Sherr
Journal:  Nat Rev Cancer       Date:  2006-08-17       Impact factor: 60.716

Review 2.  Toward clinical application of the Keap1-Nrf2 pathway.

Authors:  Takafumi Suzuki; Hozumi Motohashi; Masayuki Yamamoto
Journal:  Trends Pharmacol Sci       Date:  2013-05-09       Impact factor: 14.819

Review 3.  Role of nrf2 in oxidative stress and toxicity.

Authors:  Qiang Ma
Journal:  Annu Rev Pharmacol Toxicol       Date:  2013       Impact factor: 13.820

4.  Ferroptosis as a p53-mediated activity during tumour suppression.

Authors:  Le Jiang; Ning Kon; Tongyuan Li; Shang-Jui Wang; Tao Su; Hanina Hibshoosh; Richard Baer; Wei Gu
Journal:  Nature       Date:  2015-03-18       Impact factor: 49.962

Review 5.  NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer.

Authors:  John D Hayes; Michael McMahon
Journal:  Trends Biochem Sci       Date:  2009-03-25       Impact factor: 13.807

6.  Epigenetic Control of NRF2-Directed Cellular Antioxidant Status in Dictating Life-Death Decisions.

Authors:  John D Hayes; Albena T Dinkova-Kostova
Journal:  Mol Cell       Date:  2017-10-05       Impact factor: 17.970

7.  NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression.

Authors:  Delin Chen; Omid Tavana; Bo Chu; Luke Erber; Yue Chen; Richard Baer; Wei Gu
Journal:  Mol Cell       Date:  2017-10-05       Impact factor: 17.970

Review 8.  The emerging role of the Nrf2-Keap1 signaling pathway in cancer.

Authors:  Melba C Jaramillo; Donna D Zhang
Journal:  Genes Dev       Date:  2013-10-15       Impact factor: 11.361

9.  Collecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation.

Authors:  Jianmin Wang; Antonios Papanicolau-Sengos; Sreenivasulu Chintala; Lei Wei; Biao Liu; Qiang Hu; Kiersten Marie Miles; Jeffrey M Conroy; Sean T Glenn; Manuela Costantini; Cristina Magi-Galluzzi; Sabina Signoretti; Toni Choueiri; Michele Gallucci; Steno Sentinelli; Vito M Fazio; Maria Luana Poeta; Song Liu; Carl Morrison; Roberto Pili
Journal:  Oncotarget       Date:  2016-05-24

10.  Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis.

Authors:  Jong-Lyel Roh; Eun Hye Kim; Hyejin Jang; Daiha Shin
Journal:  Redox Biol       Date:  2016-12-18       Impact factor: 11.799
  10 in total
  2 in total

1.  Protective Effects of Ferulic Acid on Deoxynivalenol-Induced Toxicity in IPEC-J2 Cells.

Authors:  Xiangyi Meng; Wenyan Yu; Nuo Duan; Zhouping Wang; Yingbin Shen; Shijia Wu
Journal:  Toxins (Basel)       Date:  2022-04-12       Impact factor: 5.075

2.  Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.

Authors:  Jinliang Liu; Qiang Wu; Tao Yang; Feiyan Yang; Tianyi Guo; Yaping Zhou; Shuai Han; Yi Luo; Ting Guo; Feijun Luo; Qinlu Lin
Journal:  Oxid Med Cell Longev       Date:  2021-09-29       Impact factor: 6.543
  2 in total

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