Literature DB >> 30249699

Enterobacter cloacae Complex Sequence Type 171 Isolates Expressing KPC-4 Carbapenemase Recovered from Canine Patients in Ohio.

Joshua B Daniels1, Liang Chen2, Susan V Grooters3, Dixie F Mollenkopf3, Dimitria A Mathys3, Preeti Pancholi4, Barry N Kreiswirth2, Thomas E Wittum3.   

Abstract

Companion animals are likely relevant in the transmission of antimicrobial-resistant bacteria. Enterobacter xiangfangensis sequence type 171 (ST171), a clone that has been implicated in clusters of infections in humans, was isolated from two dogs with clinical disease in Ohio. The canine isolates contained IncHI2 plasmids encoding bla KPC-4 Whole-genome sequencing was used to put the canine isolates in phylogenetic context with available human ST171 sequences, as well as to characterize their bla KPC-4 plasmids.
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  antibiotic resistance; carbapenemase; plasmid-mediated resistance; veterinary microbiology

Mesh：

Substances：

Year:  2018        PMID： 30249699      PMCID： PMC6256759          DOI： 10.1128/AAC.01161-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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