| Literature DB >> 30247210 |
Roberto A Salas Fragomeni, Kenneth J Pienta1, Martin G Pomper, Michael A Gorin, Steven P Rowe.
Abstract
Recent PET imaging of glioblastoma multiforme and other high-grade gliomas using prostate-specific membrane antigen (PSMA)-targeted small-molecule radiotracers suggests a role for these agents in diagnostic imaging of recurrent/residual tumor and that PSMA-targeted endoradiotherapies may provide a new approach to therapy for patients with these difficult-to-treat tumors. We present a case of cerebral radionecrosis demonstrating PSMA-targeted radiotracer uptake. Our findings may represent a potential pitfall and limitation to the diagnostic application of PSMA-targeted agents for high-grade gliomas.Entities:
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Year: 2018 PMID: 30247210 DOI: 10.1097/RLU.0000000000002280
Source DB: PubMed Journal: Clin Nucl Med ISSN: 0363-9762 Impact factor: 7.794