| Literature DB >> 30246812 |
Chen Zeng1, Fanghao Hu, Rong Long, Wei Min.
Abstract
Stimulated Raman Scattering (SRS) coupled with alkyne tags has been an emerging imaging technique to visualize small-molecule species with high sensitivity and specificity. Here we describe the development of a ratiometric Raman probe for visualizing hydrogen sulfide (H2S) species in living cells as the first alkyne-based sensor for SRS microscopy. This probe uses an azide unit as a selective reactive site, and it targets mitochondria with high specificity. The SRS ratiometric images show a strong response to H2S level changes in living cells.Entities:
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Year: 2018 PMID: 30246812 PMCID: PMC6249677 DOI: 10.1039/c8an00910d
Source DB: PubMed Journal: Analyst ISSN: 0003-2654 Impact factor: 4.616