Literature DB >> 30245777

The evaluation of malignant mucosal melanoma of nasal cavity with a rare occasion.

Ahmet H Kepekci1, Cenk Kig2, Gul I Gundogan3.   

Abstract

Malignant mucosal melanoma is an uncommon disease with a low rate of survival. Malignancies of nasal mucosa which usually presents with nasal obstruction, epistaxis and back drip are difficult to treat and often have poor prognosis. The present case had presented to our clinic with classic symptoms and diagnostic findings of nasal polyposis. Consistently, the patient had previously been diagnosed with and treated for nasal polyposis in another ENT clinic. Physical examination, rhinoscopic examination, computed tomography (CT) scan of the head did not reveal any findings which might imply malignant formations. The operation had been planned for nasal polypectomy and taking deep biopsy specimens. The incised mass showed characteristic features of malignant tissues and the pathology report of the biopsy samples revealed that the specimen showed the histological signs of malignancy. Based on physical examination, CT findings and pathology reports the case was diagnosed as nasal mucosal melanoma. Following an oncosurgical operation, postoperative radio-therapy and chemotherapy were given to the patient and PET/CT examination of the patient did not indicate distant metastases.

Entities:  

Keywords:  Malignant mucosal melanoma; back drip; epistaxis; nasal obstruction; nasal polyposis

Year:  2018        PMID: 30245777      PMCID: PMC6146177     

Source DB:  PubMed          Journal:  Int J Physiol Pathophysiol Pharmacol        ISSN: 1944-8171


  17 in total

Review 1.  Mucosal melanoma of the head and neck: a systematic review of the literature.

Authors:  Stanislav Lazarev; Vishal Gupta; Kenneth Hu; Louis B Harrison; Richard Bakst
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-12-01       Impact factor: 7.038

2.  Giant Primary Sinonasal Mucosal Melanoma: A Rare Malignancy.

Authors:  Mehtab Alam; Mohd Aslam; Piyush Kant Singh; Shahab Farkhund Hashmi; Syed Abrar Hasan
Journal:  Gulf J Oncolog       Date:  2017-05

3.  Malignant mucosal melanoma of the paranasal sinuses: Two case presentations.

Authors:  Anna Gasparyan; Farzad Amiri; Joseph Safdieh; Vincent Reid; Elizabeth Cirincione; Dhiru Shah
Journal:  World J Clin Oncol       Date:  2011-10-10

4.  The role of postoperative adjuvant radiation therapy in the treatment of mucosal melanomas of the head and neck region.

Authors:  Jonathan M Owens; Dianna B Roberts; Jeffrey N Myers
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2003-08

Review 5.  Update on primary head and neck mucosal melanoma.

Authors:  Fernando López; Juan P Rodrigo; Antonio Cardesa; Asterios Triantafyllou; Kenneth O Devaney; William M Mendenhall; Missak Haigentz; Primož Strojan; Phillip K Pellitteri; Carol R Bradford; Ashok R Shaha; Jennifer L Hunt; Remco de Bree; Robert P Takes; Alessandra Rinaldo; Alfio Ferlito
Journal:  Head Neck       Date:  2015-05-22       Impact factor: 3.147

6.  Primary mucosal melanoma of the head and neck. Comparison of clinical presentation and histopathologic features of oral and sinonasal melanoma.

Authors:  Nicolas McLean; Mourad Tighiouart; Susan Muller
Journal:  Oral Oncol       Date:  2008-04-08       Impact factor: 5.337

7.  Epithelial markers in malignant melanoma. A study of primary lesions and their metastases.

Authors:  O Ben-Izhak; P Stark; R Levy; R Bergman; C Lichtig
Journal:  Am J Dermatopathol       Date:  1994-06       Impact factor: 1.533

8.  Melanin content in melanoma metastases affects the outcome of radiotherapy.

Authors:  Anna A Brożyna; Wojciech Jóźwicki; Krzysztof Roszkowski; Jan Filipiak; Andrzej T Slominski
Journal:  Oncotarget       Date:  2016-04-05

9.  Sinonasal Melanoma: A Case Report and Literature Review.

Authors:  I S S Alves; L G S Berriel; R T Alves; M B Pinto; C F P Oliveira; A C Cazzotto; W V Moura
Journal:  Case Rep Oncol Med       Date:  2017-01-31

10.  Recurrence in a patient with a 10-year history of sinonasal mucosal melanoma manifesting as facial swelling.

Authors:  Eleni-Marina Kalogirou; Demos Kalyvas; Konstantinos I Tosios; Kostas Tsiklakis; Alexandra Sklavounou
Journal:  J Clin Exp Dent       Date:  2017-12-01
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