Literature DB >> 30244974

Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects.

Ismail Syed1, Jennifer Lee1, Odile D Peroni1, Mark M Yore1, Pedro M Moraes-Vieira2, Anna Santoro1, Kerry Wellenstein1, Ulf Smith3, Timothy E McGraw4, Alan Saghatelian5, Barbara B Kahn6.   

Abstract

PAHSAs are anti-diabetic and anti-inflammatory lipids. Syed et al. identify numerous experimental differences that likely account for the failure of Pflimlin et al. to observe PAHSA beneficial effects. The differences include different HFDs resulting in minimal/no glucose intolerance, different assay conditions, an LC-MS protocol that was not validated, and use of olive oil, a bioactive nutrient that improves glucose tolerance, as a vehicle.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30244974      PMCID： PMC6542592          DOI： 10.1016/j.cmet.2018.09.007

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  17 in total

Review 1.  Solubilizing excipients in oral and injectable formulations.

Authors:  Robert G Strickley
Journal:  Pharm Res       Date:  2004-02       Impact factor: 4.200

2.  Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements.

Authors:  Matthew J Kolar; Andrew T Nelson; Tina Chang; Meric Erikci Ertunc; Mitchell P Christy; Lena Ohlsson; Magnus Härröd; Barbara B Kahn; Dionicio Siegel; Alan Saghatelian
Journal:  Anal Chem       Date:  2018-03-26       Impact factor: 6.986

3.  A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids.

Authors:  Tejia Zhang; Shili Chen; Ismail Syed; Marcus Ståhlman; Matthew J Kolar; Edwin A Homan; Qian Chu; Ulf Smith; Jan Borén; Barbara B Kahn; Alan Saghatelian
Journal:  Nat Protoc       Date:  2016-03-17       Impact factor: 13.491

4.  Comprehensive Screening and Identification of Fatty Acid Esters of Hydroxy Fatty Acids in Plant Tissues by Chemical Isotope Labeling-Assisted Liquid Chromatography-Mass Spectrometry.

Authors:  Quan-Fei Zhu; Jing-Wen Yan; Tian-Yi Zhang; Hua-Ming Xiao; Yu-Qi Feng
Journal:  Anal Chem       Date:  2018-08-10       Impact factor: 6.986

5.  Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1.

Authors:  A S Rocca; J LaGreca; J Kalitsky; P L Brubaker
Journal:  Endocrinology       Date:  2001-03       Impact factor: 4.736

6.  Nrf2-Mediated Antioxidant Defense and Peroxiredoxin 6 Are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid.

Authors:  Ondrej Kuda; Marie Brezinova; Jan Silhavy; Vladimir Landa; Vaclav Zidek; Chandra Dodia; Franziska Kreuchwig; Marek Vrbacky; Laurence Balas; Thierry Durand; Norbert Hübner; Aron B Fisher; Jan Kopecky; Michal Pravenec
Journal:  Diabetes       Date:  2018-03-16       Impact factor: 9.461

7.  Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

Authors:  Ismail Syed; Jennifer Lee; Pedro M Moraes-Vieira; Cynthia J Donaldson; Alexandra Sontheimer; Pratik Aryal; Kerry Wellenstein; Matthew J Kolar; Andrew T Nelson; Dionicio Siegel; Jacek Mokrosinski; I Sadaf Farooqi; Juan Juan Zhao; Mark M Yore; Odile D Peroni; Alan Saghatelian; Barbara B Kahn
Journal:  Cell Metab       Date:  2018-02-06       Impact factor: 27.287

8.  Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.

Authors:  Mark M Yore; Ismail Syed; Pedro M Moraes-Vieira; Tejia Zhang; Mark A Herman; Edwin A Homan; Rajesh T Patel; Jennifer Lee; Shili Chen; Odile D Peroni; Abha S Dhaneshwar; Ann Hammarstedt; Ulf Smith; Timothy E McGraw; Alan Saghatelian; Barbara B Kahn
Journal:  Cell       Date:  2014-10-09       Impact factor: 41.582

9.  Docosahexaenoic Acid-Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties.

Authors:  Ondrej Kuda; Marie Brezinova; Martina Rombaldova; Barbora Slavikova; Martin Posta; Petr Beier; Petra Janovska; Jiri Veleba; Jan Kopecky; Eva Kudova; Terezie Pelikanova; Jan Kopecky
Journal:  Diabetes       Date:  2016-06-16       Impact factor: 9.461

10.  An in silico MS/MS library for automatic annotation of novel FAHFA lipids.

Authors:  Yan Ma; Tobias Kind; Arpana Vaniya; Ingrid Gennity; Johannes F Fahrmann; Oliver Fiehn
Journal:  J Cheminform       Date:  2015-11-16       Impact factor: 5.514
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  13 in total

1.  PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms.

Authors:  Peng Zhou; Anna Santoro; Odile D Peroni; Andrew T Nelson; Alan Saghatelian; Dionicio Siegel; Barbara B Kahn
Journal:  J Clin Invest       Date:  2019-10-01       Impact factor: 14.808

2.  Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice.

Authors:  Veronika Paluchova; Marina Oseeva; Marie Brezinova; Tomas Cajka; Kristina Bardova; Katerina Adamcova; Petr Zacek; Kristyna Brejchova; Laurence Balas; Hana Chodounska; Eva Kudova; Renate Schreiber; Rudolf Zechner; Thierry Durand; Martin Rossmeisl; Nada A Abumrad; Jan Kopecky; Ondrej Kuda
Journal:  Diabetes       Date:  2019-12-05       Impact factor: 9.461

3.  Adipose Tissue Lipokines: Recent Progress and Future Directions.

Authors:  Veronica L Li; Joon T Kim; Jonathan Z Long
Journal:  Diabetes       Date:  2020-12       Impact factor: 9.461

4.  Long-term intake of 9-PAHPA or 9-OAHPA modulates favorably the basal metabolism and exerts an insulin sensitizing effect in obesogenic diet-fed mice.

Authors:  Melha Benlebna; Laurence Balas; Béatrice Bonafos; Laurence Pessemesse; Gilles Fouret; Claire Vigor; Sylvie Gaillet; Jacques Grober; Florence Bernex; Jean-François Landrier; Ondrej Kuda; Thierry Durand; Charles Coudray; François Casas; Christine Feillet-Coudray
Journal:  Eur J Nutr       Date:  2020-09-28       Impact factor: 5.614

5.  PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice.

Authors:  Ismail Syed; Maria F Rubin de Celis; James F Mohan; Pedro M Moraes-Vieira; Archana Vijayakumar; Andrew T Nelson; Dionicio Siegel; Alan Saghatelian; Diane Mathis; Barbara B Kahn
Journal:  J Clin Invest       Date:  2019-08-05       Impact factor: 14.808

Review 6.  The endocrine function of adipose tissues in health and cardiometabolic disease.

Authors:  Ludger Scheja; Joerg Heeren
Journal:  Nat Rev Endocrinol       Date:  2019-07-11       Impact factor: 43.330

Review 7.  Inter-organ cross-talk in metabolic syndrome.

Authors:  Christina Priest; Peter Tontonoz
Journal:  Nat Metab       Date:  2019-12-09

Review 8.  Insulin action in adipocytes, adipose remodeling, and systemic effects.

Authors:  Anna Santoro; Timothy E McGraw; Barbara B Kahn
Journal:  Cell Metab       Date:  2021-04-06       Impact factor: 27.287

Review 9.  Analytical Methods for the Determination of Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) in Biological Samples, Plants and Foods.

Authors:  Maroula G Kokotou
Journal:  Biomolecules       Date:  2020-07-22

Review 10.  Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics.

Authors:  Pauline Morigny; Jeremie Boucher; Peter Arner; Dominique Langin
Journal:  Nat Rev Endocrinol       Date:  2021-02-24       Impact factor: 43.330
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