Sarra Gattoussi1,2, Gabriëlle H S Buitendijk3,4, Tunde Peto5, Irene Leung6, Steffen Schmitz-Valckenberg7, Akio Oishi8, Sebastian Wolf9, Gábor Deák10, Cécile Delcourt1, Caroline C W Klaver3,4, Jean-François Korobelnik1,2. 1. Bordeaux Population Health Research Center, Team LEHA, UMR 1219, Inserm, University of Bordeaux, Bordeaux, France. 2. Service d'Ophtalmologie, CHU de Bordeaux, Bordeaux, France. 3. Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands. 4. Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands. 5. School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast, UK. 6. Department of Research and Development, Moorfields Eye Hospital NHS Foundation Trust, London, UK. 7. GRADE Reading Center, Department of Ophthalmology, University of Bonn, Bonn, Germany. 8. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. 9. Bern Photographic Reading Center, Department of Ophthalmology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland. 10. Vienna Reading Center, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Abstract
PURPOSE: The aim of the European Eye Epidemiology (E3) consortium was to develop a spectral-domain optical coherence tomography (SD-OCT)-based classification for macular diseases to standardize epidemiological studies. METHODS: A European panel of vitreoretinal disease experts and epidemiologists belonging to the E3 consortium was assembled to define a classification for SD-OCT imaging of the macula. A series of meeting was organized, to develop, test and finalize the classification. First, grading methods used by the different research groups were presented and discussed, and a first version of classification was proposed. This first version was then tested on a set of 50 SD-OCT images in the Bordeaux and Rotterdam centres. Agreements were analysed and discussed with the panel of experts and a final version of the classification was produced. RESULTS: Definitions and classifications are proposed for the structure assessment of the vitreomacular interface (visibility of vitreous interface, vitreomacular adhesion, vitreomacular traction, epiretinal membrane, full-thickness macular hole, lamellar macular hole, macular pseudo-hole) and of the retina (retinoschisis, drusen, pigment epithelium detachment, hyper-reflective clumps, retinal pigment epithelium atrophy, intraretinal cystoid spaces, intraretinal tubular changes, subretinal fluid, subretinal material). Classifications according to size and location are defined. Illustrations of each item are provided, as well as the grading form. CONCLUSION: The E3 SD-OCT classification has been developed to harmonize epidemiological studies. This homogenization will allow comparing and sharing data collection between European and international studies.
PURPOSE: The aim of the European Eye Epidemiology (E3) consortium was to develop a spectral-domain optical coherence tomography (SD-OCT)-based classification for macular diseases to standardize epidemiological studies. METHODS: A European panel of vitreoretinal disease experts and epidemiologists belonging to the E3 consortium was assembled to define a classification for SD-OCT imaging of the macula. A series of meeting was organized, to develop, test and finalize the classification. First, grading methods used by the different research groups were presented and discussed, and a first version of classification was proposed. This first version was then tested on a set of 50 SD-OCT images in the Bordeaux and Rotterdam centres. Agreements were analysed and discussed with the panel of experts and a final version of the classification was produced. RESULTS: Definitions and classifications are proposed for the structure assessment of the vitreomacular interface (visibility of vitreous interface, vitreomacular adhesion, vitreomacular traction, epiretinal membrane, full-thickness macular hole, lamellar macular hole, macular pseudo-hole) and of the retina (retinoschisis, drusen, pigment epithelium detachment, hyper-reflective clumps, retinal pigment epithelium atrophy, intraretinal cystoid spaces, intraretinal tubular changes, subretinal fluid, subretinal material). Classifications according to size and location are defined. Illustrations of each item are provided, as well as the grading form. CONCLUSION: The E3 SD-OCT classification has been developed to harmonize epidemiological studies. This homogenization will allow comparing and sharing data collection between European and international studies.
Authors: Jason N Crosson; Thomas A Swain; Mark E Clark; Carrie E Huisingh; Gerald McGwin; Cynthia Owsley; Christine A Curcio Journal: Ophthalmol Retina Date: 2019-03-30
Authors: Christiana Diana Maria Dragosloveanu; Nicoleta Zamfiroiu-Avidis; Şerban Dragosloveanu; Mihai Adrian Păsărică; Cătălina Ioana Tătaru; Paul Filip Curcă Journal: Rom J Morphol Embryol Date: 2021 Oct-Dec Impact factor: 0.833
Authors: Eric F Thee; Magda A Meester-Smoor; Daniel T Luttikhuizen; Johanna M Colijn; Clair A Enthoven; Annechien E G Haarman; Dimitris Rizopoulos; Caroline C W Klaver Journal: Transl Vis Sci Technol Date: 2020-04-24 Impact factor: 3.283