Avik Chatterjee1, Jennifer W Thompson2, Katherine Svensson3, Marcela Tamayo Y Ortiz4, Robert Wright5, Rosalind Wright5, Martha Tellez-Rojo6, Andrea Baccarelli7, Alejandra Cantoral6, Lourdes Schnaas8, Emily Oken2. 1. Division of Global Health Equity, Department of Internal Medicine, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115. Electronic address: avc031@mail.harvard.edu. 2. Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Dr, Suite 401E, Boston, MA 02215. 3. Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1057, New York, NY, 10029. 4. Center for Nutrition and Health Research, National Institute of Public Health, Universidad No. 655 Colonia Santa María Ahuacatitlán, Cerrada Los Pinos y Caminera CP, 62100, Cuernavaca, Morelos. México; Mexican Council for Science and Technology, National Institute of Public Health Mexico, Universidad No. 655 Colonia Santa María Ahuacatitlán, Cerrada Los Pinos y Caminera CP, 62100, Cuernavaca, Morelos. México. 5. Kravis Children's Hospital, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1057, New York, NY, 10029; Mailman School of Public Health, Columbia University, 722 W 168th St, NY, NY 10032. 6. Center for Nutrition and Health Research, National Institute of Public Health, Universidad No. 655 Colonia Santa María Ahuacatitlán, Cerrada Los Pinos y Caminera CP, 62100, Cuernavaca, Morelos. México. 7. Mailman School of Public Health, Columbia University, 722 W 168th St, NY, NY 10032. 8. National Institute of Perinatology, Calle Montes Urales 800, Miguel Hidalgo, Lomas Virreyes, 11000 Ciudad de México, CDMX, Mexico.
Abstract
STUDY OBJECTIVES: Maternal antenatal stress may influence offspring development and behavior, but any association with child sleep is unknown. METHODS: From 2007 to 2011, we recruited pregnant women in Mexico City to the Programming Research in Obesity, Growth, Environment, and Social Stressors prebirth cohort. Mothers completed the Perceived Stress Scale (PSS, a 4-item questionnaire assessing past-month stress) and the Crisis in Family Systems measure assessing negative life events (NLEs; how many domains among the 11 assessed in which the mother experienced a stressful event in the prior 6 months)-with higher scores reflecting higher stress-and provided 5 timed salivary samples per day on 2 consecutive days, from which we derived cortisol area under the curve, slope, and awakening response. At age 4-6 years, children's sleep was estimated using accelerometry over a 7-day period. We performed secondary analysis of associations of antenatal maternal stress with child sleep duration and efficiency (time asleep/time in bed) using linear regression adjusted for maternal and child characteristics. RESULTS: Among 594 mother-child dyads, mean antenatal PSS score was 5.2 (SD = 3.2) out of 16, and mean NLE was 3.2 (SD = 2) out of 11; child sleep duration was 7.7 hours (SD = 0.7), and sleep efficiency was 79% (SD = 6). There was no association between any of the stress measures-PSS, NLE, or salivary cortisol-and sleep duration or sleep efficiency in adjusted or unadjusted models. CONCLUSIONS: Among mother-child dyads in a Mexico City cohort, antenatal stress was not associated with important changes in child sleep at 4-6 years.
STUDY OBJECTIVES: Maternal antenatal stress may influence offspring development and behavior, but any association with child sleep is unknown. METHODS: From 2007 to 2011, we recruited pregnant women in Mexico City to the Programming Research in Obesity, Growth, Environment, and Social Stressors prebirth cohort. Mothers completed the Perceived Stress Scale (PSS, a 4-item questionnaire assessing past-month stress) and the Crisis in Family Systems measure assessing negative life events (NLEs; how many domains among the 11 assessed in which the mother experienced a stressful event in the prior 6 months)-with higher scores reflecting higher stress-and provided 5 timed salivary samples per day on 2 consecutive days, from which we derived cortisol area under the curve, slope, and awakening response. At age 4-6 years, children's sleep was estimated using accelerometry over a 7-day period. We performed secondary analysis of associations of antenatal maternal stress with child sleep duration and efficiency (time asleep/time in bed) using linear regression adjusted for maternal and child characteristics. RESULTS: Among 594 mother-child dyads, mean antenatal PSS score was 5.2 (SD = 3.2) out of 16, and mean NLE was 3.2 (SD = 2) out of 11; child sleep duration was 7.7 hours (SD = 0.7), and sleep efficiency was 79% (SD = 6). There was no association between any of the stress measures-PSS, NLE, or salivary cortisol-and sleep duration or sleep efficiency in adjusted or unadjusted models. CONCLUSIONS: Among mother-child dyads in a Mexico City cohort, antenatal stress was not associated with important changes in child sleep at 4-6 years.
Authors: Melanie Zinkhan; Klaus Berger; Sabrina Hense; Maren Nagel; Anne Obst; Beate Koch; Thomas Penzel; Ingo Fietze; Wolfgang Ahrens; Peter Young; Svenja Happe; Jan W Kantelhardt; Alexander Kluttig; Andrea Schmidt-Pokrzywniak; Frank Pillmann; Andreas Stang Journal: Sleep Med Date: 2014-05-28 Impact factor: 3.492
Authors: Shalini Paruthi; Lee J Brooks; Carolyn D'Ambrosio; Wendy A Hall; Suresh Kotagal; Robin M Lloyd; Beth A Malow; Kiran Maski; Cynthia Nichols; Stuart F Quan; Carol L Rosen; Matthew M Troester; Merrill S Wise Journal: J Clin Sleep Med Date: 2016-06-15 Impact factor: 4.062
Authors: Sandy Wong; Alejandra Cantoral; Martha María Téllez-Rojo; Ivan Pantic; Emily Oken; Katherine Svensson; Michael Dorman; Iván Gutiérrez-Avila; Johnathan Rush; Nia McRae; Robert O Wright; Andrea A Baccarelli; Itai Kloog; Allan C Just Journal: PLoS One Date: 2020-10-30 Impact factor: 3.240