Literature DB >> 30240184

Shared Platform for Antibiotic Research and Knowledge: A Collaborative Tool to SPARK Antibiotic Discovery.

Joe Thomas1, Marc Navre2, Aileen Rubio3, Allan Coukell1.   

Abstract

The discovery of urgently needed antibiotics is hindered by challenges to information sharing. To help address this challenge, The Pew Charitable Trusts launched SPARK: the Shared Platform for Antibiotic Research and Knowledge. SPARK is an online, publicly available, interactive database designed to help scientists build on previous research and generate new insights to advance the field's understanding of Gram-negative permeability. This Viewpoint details how data are selected and integrated into the platform, how scientists can use SPARK to share their data, and the ways the scientific community can access and use these data to develop hypotheses.

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Year:  2018        PMID: 30240184     DOI: 10.1021/acsinfecdis.8b00193

Source DB:  PubMed          Journal:  ACS Infect Dis        ISSN: 2373-8227            Impact factor:   5.084


  5 in total

Review 1.  Machine Learning in Antibacterial Drug Design.

Authors:  Marko Jukič; Urban Bren
Journal:  Front Pharmacol       Date:  2022-05-03       Impact factor: 5.988

2.  Property space mapping of Pseudomonas aeruginosa permeability to small molecules.

Authors:  Inga V Leus; Jon W Weeks; Vincent Bonifay; Yue Shen; Liang Yang; Connor J Cooper; Dinesh Nash; Adam S Duerfeldt; Jeremy C Smith; Jerry M Parks; Valentin V Rybenkov; Helen I Zgurskaya
Journal:  Sci Rep       Date:  2022-05-17       Impact factor: 4.996

3.  Ideation and implementation of an open science drug discovery business model - M4K Pharma.

Authors:  Maxwell Robert Morgan; Owen Gwilym Roberts; Aled Morgan Edwards
Journal:  Wellcome Open Res       Date:  2018-12-06

Review 4.  Functional and Material Properties in Nanocatalyst Design: A Data Handling and Sharing Problem.

Authors:  Daniel Lach; Uladzislau Zhdan; Adam Smolinski; Jaroslaw Polanski
Journal:  Int J Mol Sci       Date:  2021-05-13       Impact factor: 5.923

5.  There is no market for new antibiotics: this allows an open approach to research and development.

Authors:  Dana M Klug; Fahima I M Idiris; Mark A T Blaskovich; Frank von Delft; Christopher G Dowson; Claas Kirchhelle; Adam P Roberts; Andrew C Singer; Matthew H Todd
Journal:  Wellcome Open Res       Date:  2021-06-11
  5 in total

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