Literature DB >> 3023907

Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.

J S Lebkowski, J H Miller, M P Calos.   

Abstract

The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.

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Year:  1986        PMID： 3023907      PMCID： PMC367715          DOI： 10.1128/mcb.6.5.1838-1842.1986

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  25 in total

1.  Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA.

Authors:  J W Nicoll; P F Swann; A E Pegg
Journal:  Nature       Date:  1975-03-20       Impact factor: 49.962

2.  Characteristics of a human cell line transformed by DNA from human adenovirus type 5.

Authors:  F L Graham; J Smiley; W C Russell; R Nairn
Journal:  J Gen Virol       Date:  1977-07       Impact factor: 3.891

3.  A new pathway for DNA repair in Escherichia coli.

Authors:  L Samson; J Cairns
Journal:  Nature       Date:  1977-05-19       Impact factor: 49.962

4.  Specific induction of transitions and transversions of G-C base pairs by 4-nitroquinoline-1-oxide in iso-1-cytochrome c mutants of yeast.

Authors:  L Prakash; J W Stewart; F Sherman
Journal:  J Mol Biol       Date:  1974-05-05       Impact factor: 5.469

5.  Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.

Authors:  L A Chasin
Journal:  Cell       Date:  1974-05       Impact factor: 41.582

6.  Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.

Authors:  E H Chu; H V Malling
Journal:  Proc Natl Acad Sci U S A       Date:  1968-12       Impact factor: 11.205

Review 7.  Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

Authors:  E M Witkin
Journal:  Bacteriol Rev       Date:  1976-12

8.  Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residues.

Authors:  C Coulondre; J H Miller
Journal:  J Mol Biol       Date:  1977-12-15       Impact factor: 5.469

9.  The lacI shuttle: rapid analysis of the mutagenic specificity of ultraviolet light in human cells.

Authors:  J S Lebkowski; S Clancy; J H Miller; M P Calos
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

10.  An adaptive response of E. coli to low levels of alkylating agent: comparison with previously characterised DNA repair pathways.

Authors:  P Jeggo; T M Defais; L Samson; P Schendel
Journal:  Mol Gen Genet       Date:  1977-11-29
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  14 in total

1.  Mouse transgenes in human cells detect specific base substitutions.

Authors:  D A Schaff; R A Jarrett; S R Dlouhy; S Ponniah; M Stockelman; P J Stambrook; J A Tischfield
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

2.  A deletion common to two independently derived waxy mutations of maize.

Authors:  R J Okagaki; M G Neuffer; S R Wessler
Journal:  Genetics       Date:  1991-06       Impact factor: 4.562

3.  Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase.

Authors:  K S Ellison; E Dogliotti; T D Connors; A K Basu; J M Essigmann
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

4.  Genetic definition of ras effector elements.

Authors:  J C Stone; R A Blanchard
Journal:  Mol Cell Biol       Date:  1991-12       Impact factor: 4.272

5.  Kinds of mutations formed when a shuttle vector containing adducts of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene replicates in human cells.

Authors:  J L Yang; V M Maher; J J McCormick
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

6.  A substitution mutation in OsCCD7 cosegregates with dwarf and increased tillering phenotype in rice.

Authors:  Krishnanand P Kulkarni; Chandrapal Vishwakarma; Sarada P Sahoo; John M Lima; Manoj Nath; Prasad Dokku; Rajesh N Gacche; Trilochan Mohapatra; S Robin; N Sarla; M Seshashayee; Ashok K Singh; Kuldeep Singh; Nagendra K Singh; R P Sharma
Journal:  J Genet       Date:  2014-08       Impact factor: 1.166

7.  Kinds and spectrum of mutations induced by 1-nitrosopyrene adducts during plasmid replication in human cells.

Authors:  J L Yang; V M Maher; J J McCormick
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

8.  Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

Authors:  R B DuBridge; P Tang; H C Hsia; P M Leong; J H Miller; M P Calos
Journal:  Mol Cell Biol       Date:  1987-01       Impact factor: 4.272

9.  Mutational specificity of ethyl methanesulfonate in excision-repair-proficient and -deficient strains of Drosophila melanogaster.

Authors:  A Pastink; E Heemskerk; M J Nivard; C J van Vliet; E W Vogel
Journal:  Mol Gen Genet       Date:  1991-10

10.  Molecular analysis of ethyl methanesulfonate-induced reversion of a chromosomally integrated mutant shuttle vector gene in mammalian cells.

Authors:  J A Greenspan; F M Xu; R L Davidson
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272
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