Piotr Duchnowski1, Tomasz Hryniewiecki2, Mariusz Kuśmierczyk3, Piotr Szymański2. 1. Department of Acquired Cardiac Defects, Institute of Cardiology, Alpejska 42, Warsaw, Poland. duchnowski@vp.pl. 2. Department of Acquired Cardiac Defects, Institute of Cardiology, Alpejska 42, Warsaw, Poland. 3. Department of Cardiosurgery and Transplantology, Institute of Cardiology, Warsaw, Poland.
Abstract
BACKGROUND: The aim of the study was to investigate the prognostic value of selected biomarkers in patients with aortic regurgitation undergoing valve surgery. METHODS: A prospective study was conducted on a group of consecutive patients with hemodynamically significant aortic regurgitation that underwent elective aortic valve surgery. The primary endpoint was 30-day mortality and any major adverse event within 30 days. RESULTS: The study group included 205 consecutive patients who underwent replacement or repair of the aortic valve. The primary endpoint occurred in 72 patients. At multivariate analysis red cell distribution width (RDW; p = 0.03) and high-sensitivity troponin T (hs-TnT; p = 0.02) remained independent predictors of the major complications including death. CONCLUSIONS: Elevated preoperative RDW and hs-TnT were associated with a poorer outcome following aortic valve surgery.
BACKGROUND: The aim of the study was to investigate the prognostic value of selected biomarkers in patients with aortic regurgitation undergoing valve surgery. METHODS: A prospective study was conducted on a group of consecutive patients with hemodynamically significant aortic regurgitation that underwent elective aortic valve surgery. The primary endpoint was 30-day mortality and any major adverse event within 30 days. RESULTS: The study group included 205 consecutive patients who underwent replacement or repair of the aortic valve. The primary endpoint occurred in 72 patients. At multivariate analysis red cell distribution width (RDW; p = 0.03) and high-sensitivity troponin T (hs-TnT; p = 0.02) remained independent predictors of the major complications including death. CONCLUSIONS: Elevated preoperative RDW and hs-TnT were associated with a poorer outcome following aortic valve surgery.
Authors: Larry A Allen; G Michael Felker; Mandeep R Mehra; Jun R Chiong; Stephanie H Dunlap; Jalal K Ghali; Daniel J Lenihan; Ron M Oren; Lynne E Wagoner; Todd A Schwartz; Kirkwood F Adams Journal: J Card Fail Date: 2009-12-29 Impact factor: 5.712
Authors: Zofia Grąbczewska; Robert Dębski; Krzysztof Góralczyk; Adam Sukiennik; Iwona Świątkiewicz; Jacek Kubica Journal: Pol Arch Med Wewn Date: 2015-01-30
Authors: John T Parissis; John Papadakis; Nikolaos P E Kadoglou; Christos Varounis; Panagiotis Psarogiannakopoulos; Penelope Rafouli-Stergiou; Ignatios Ikonomidis; Ioannis Paraskevaidis; Ioanna Dimopoulou; Aikaterini Zerva; Kleante Dima; Maria Anastasiou-Nana; Gerasimos Filippatos Journal: Int J Cardiol Date: 2013-05-24 Impact factor: 4.164
Authors: Frank Weidemann; Sebastian Herrmann; Stefan Störk; Markus Niemann; Stefan Frantz; Volkmar Lange; Meinrad Beer; Stefan Gattenlöhner; Wolfram Voelker; Georg Ertl; Jörg M Strotmann Journal: Circulation Date: 2009-08-03 Impact factor: 29.690
Authors: Nay Aung; Rafal Dworakowski; Jonathan Byrne; Emma Alcock; Ranjit Deshpande; Kailasam Rajagopal; Beth Brickham; Mark J Monaghan; Darlington O Okonko; Olaf Wendler; Philip A Maccarthy Journal: Heart Date: 2013-06-04 Impact factor: 5.994
Authors: Piotr Duchnowski; Piotr Szymański; Ewa Orłowska-Baranowska; Mariusz Kuśmierczyk; Tomasz Hryniewiecki Journal: Kardiol Pol Date: 2015-10-27 Impact factor: 3.108