Literature DB >> 30232472

Visualization of mitochondrial DNA in living cells with super-resolution microscopy using thiophene-based terpyridine Zn(ii) complexes.

Yu Shen1, Tao Shao, Bin Fang, Wei Du, Mingzhu Zhang, Jiejie Liu, Tianyan Liu, Xiaohe Tian, Qiong Zhang, Aidong Wang, Jiaxiang Yang, Jieying Wu, Yupeng Tian.   

Abstract

We present a thiophene-based terpyridine Zn(ii) complex (namely LC) which could specifically target live cell mitochondria via binding with mitochondrial DNA (mtDNA). Due to its high biocompatibility, red emission and photo-stability, mtDNA distribution within mitochondrial cristae and inner matrix in living cells was successfully visualized using stimulated emission depletion (STED) nanoscopy with unprecedented resolution.

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Year:  2018        PMID： 30232472     DOI： 10.1039/c8cc06276e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

Review 1.  Organelle Interaction and Drug Discovery: Towards Correlative Nanoscopy and Molecular Dynamics Simulation.

Authors:  Zhiwei Yang; Zichen Zhang; Yizhen Zhao; Qiushi Ye; Xuhua Li; Lingjie Meng; Jiangang Long; Shengli Zhang; Lei Zhang
Journal:  Front Pharmacol       Date:  2022-06-20       Impact factor: 5.988

2.  Bright and Light-Up Sensing of Benzo[c,d]indole-oxazolopyridine Cyanine Dye for RNA and Its Application to Highly Sensitive Imaging of Nucleolar RNA in Living Cells.

Authors:  Kei Higuchi; Yusuke Sato; Nao Togashi; Michiyuki Suzuki; Yukina Yoshino; Seiichi Nishizawa
Journal:  ACS Omega       Date:  2022-06-29

3.  Enhanced three-photon activity triggered by the AIE behaviour of a novel terpyridine-based Zn(ii) complex bearing a thiophene bridge.

Authors:  Zhihui Feng; Dandan Li; Mingzhu Zhang; Tao Shao; Yu Shen; Xiaohe Tian; Qiong Zhang; Shengli Li; Jieying Wu; Yupeng Tian
Journal:  Chem Sci       Date:  2019-06-11       Impact factor: 9.825
  3 in total

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