| Literature DB >> 3023244 |
Abstract
When murine macrophage (M phi) monolayers are treated with cis-Platin (10 micrograms or 5 micrograms/ml) for 30 min, 1, 2, 4, 8 and 24 h a significant increase in the release of H2O2 and O-2 by M phi is observed. The release of H2O2 and O-2 was comparatively much more when M phi were treated with 5 micrograms/ml cis-Platin than 10 micrograms/ml. However, it is observed that 4 h cis-Platin treatment results in comparative inhibition in the release of H2O2 and O-2. Further, we compared the release of H2O2 and O-2 by M phi treated with cis-Platin, LPS and PMA.Entities:
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Year: 1986 PMID： 3023244 DOI： 10.1016/0192-0561(86)90006-8
Source DB: PubMed Journal: Int J Immunopharmacol ISSN： 0192-0561