| Literature DB >> 302314 |
Abstract
Antisera prepared against papain-digested spleen cell membranes were known to by cytotoxic for normal and neoplastic human B lymphocytes and for a majority of acute and chronic myeloid leukemic cells. It is now shown that these antisera are also cytotoxic for normal myeloid stem cells (CFU-C), thus providing a probable explanation for their occurrence in myeloid neoplasia.Entities:
Mesh:
Year: 1977 PMID: 302314 PMCID: PMC2180819 DOI: 10.1084/jem.146.4.1143
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307