Literature DB >> 30230293

Long-term oncologic and functional outcomes after robot-assisted partial nephrectomy in elderly patients.

Mihai D Vartolomei1,2, Deliu V Matei1,3, Giuseppe Renne4, Valeria M Tringali1, Nicolae Crișan3, Gennaro Musi1, Francesco A Mistretta1, Andrea Russo1, Andrea Conti1, Gabriele Cozzi1, Stefano Luzzago1, Michele Catellani1, Antonio Cioffi1, Giovanni Cordima1, Roberto Bianchi1, Ettore Di Trapani1, Alessandro Serino1, Maurizio Delor1, Raffaele Bianco1, Danilo Bottero1, Matteo Ferro5, Ottavio De Cobelli1,6.   

Abstract

BACKGROUND: The aim of this study was to assess the long-term oncologic and functional outcomes in elderly patients having undergone robot-assisted partial nephrectomy (RAPN) for renal cancer (RC).
METHODS: Sixty-one patients out of 323 who underwent RAPN for localized RC between July 2009 and March 2016 in our high-volume robotic surgery center (>800 procedures/year), had 70 years or more. Inclusion criteria of the study were age ≥70 years; pathological confirmed RCC and ASA Score ≤3. All patients were stratified according to PADUA classification system in three groups: <7 points, 8-9 points, >10 points. Trifecta was defined as a warm ischemia time (WIT) less then 25 min, negative surgical margins and no perioperative complications.
RESULTS: A total of 52 patients were included; median follow-up was 47 months. Median age was 74 yrs. (IQR 72-76.5). Complication rate was 15.4%. Trifecta failure was associated to PADUA Score (P=0.02), and tumor diameter (P=0.04). Renal function was altered in 10 (19.2%) patients before surgery and at last follow-up in 11 (21.1%) patients (CKD stage>2) The DFS, OS and CSS were 89.33%, 90.06% and 94.4%, respectively.
CONCLUSIONS: In a high-volume center, robot-assisted approach is feasible and safe in surgical fit elderly patients with good long-term oncologic outcomes.

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Year:  2018        PMID: 30230293     DOI: 10.23736/S0393-2249.18.03006-0

Source DB:  PubMed          Journal:  Minerva Urol Nefrol        ISSN: 0393-2249            Impact factor:   3.720


  3 in total

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2.  Efficacy and feasibility of robot-assisted partial nephrectomy for octogenarians: comparison with younger counterparts.

Authors:  Yudai Ishiyama; Tsunenori Kondo; Kazuhiko Yoshida; Junpei Iizuka; Kazunari Tanabe; Toshio Takagi
Journal:  J Robot Surg       Date:  2022-01-21

3.  Gene expression profiles and treatments for metastatic renal cell carcinoma: What does still need to be defined?

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  3 in total

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