James Rizkalla1, Matthew Jeffers2, Paul Salama2, Maher Rizkalla2,3. 1. Baylor University Medical Center, Dallas, TX, United States. 2. Department of Electrical and Computer Engineering, Indiana University Purdue University Indianapolis (IUPUI), 723 West Michigan Street, Indianapolis, Inn, 46202, United States. 3. Integrated Nanotechnology Development Institute (INDI), IUPUI, United States.
Abstract
BACKGROUND: Femoral neck fractures are common injuries managed by orthopedic surgeons across the world. From pediatrics to geriatrics, disruption of the blood supply to the femoral neck is a well-recognized source of morbidity and mortality, oftentimes resulting in avascular necrosis of the femoral head. This devastating complication occurs in 10-45% of femoral neck fractures. Therefore, it is vital for orthopedic surgeons provide efficient treatment of this injury, in order to optimize the patient's potential outcome and prevent long-term sequelae. METHODS: In this study, the anatomy of the proximal femur, including femoral metaphysis, femoral neck, vasculature, and femoral head, were simulated in COMSOL Finite Element Analysis (FEA) software. Electric fields were generated in a fashion that exploited disruptions within the vasculature of the femoral neck. This study was aimed at developing an alternative imaging modality for narrowing or disrupting the femoral neck's vasculature. The variables used for investigation included: frequency, penetration depth, and magnitude of the electrical energy. These variables, when combined, allowed for enhanced simulated visualization of the vasculature of the femoral neck and theoretically expedited diagnosis of obvious, or occult, femoral neck injury. RESULTS: Simulated blood vessels were developed in two-dimensions: the phi direction (circular), and z-direction. Two different frequencies, 3 GHz, and 5 GHz were considered, with 100-J energy pulses within blood vessels of 2.54 mm in diameter. The fat surrounding the bone to the outside surface body was simulated at 0.25 inch (0.65 cm). An additional model, with layered fat and skin above the vessels, was simulated at 2000J and successfully able to visualize the femoral neck's blood vessels. Results showed a distinguished E field across the blood boundary of nearly 170 V/M. CONCLUSIONS: The electric field simulation data within the Phi and Z directions promises the feasibility of a subsequent practical model.
BACKGROUND: Femoral neck fractures are common injuries managed by orthopedic surgeons across the world. From pediatrics to geriatrics, disruption of the blood supply to the femoral neck is a well-recognized source of morbidity and mortality, oftentimes resulting in avascular necrosis of the femoral head. This devastating complication occurs in 10-45% of femoral neck fractures. Therefore, it is vital for orthopedic surgeons provide efficient treatment of this injury, in order to optimize the patient's potential outcome and prevent long-term sequelae. METHODS: In this study, the anatomy of the proximal femur, including femoral metaphysis, femoral neck, vasculature, and femoral head, were simulated in COMSOL Finite Element Analysis (FEA) software. Electric fields were generated in a fashion that exploited disruptions within the vasculature of the femoral neck. This study was aimed at developing an alternative imaging modality for narrowing or disrupting the femoral neck's vasculature. The variables used for investigation included: frequency, penetration depth, and magnitude of the electrical energy. These variables, when combined, allowed for enhanced simulated visualization of the vasculature of the femoral neck and theoretically expedited diagnosis of obvious, or occult, femoral neck injury. RESULTS: Simulated blood vessels were developed in two-dimensions: the phi direction (circular), and z-direction. Two different frequencies, 3 GHz, and 5 GHz were considered, with 100-J energy pulses within blood vessels of 2.54 mm in diameter. The fat surrounding the bone to the outside surface body was simulated at 0.25 inch (0.65 cm). An additional model, with layered fat and skin above the vessels, was simulated at 2000J and successfully able to visualize the femoral neck's blood vessels. Results showed a distinguished E field across the blood boundary of nearly 170 V/M. CONCLUSIONS: The electric field simulation data within the Phi and Z directions promises the feasibility of a subsequent practical model.