Literature DB >> 30228503

Modern Strategies to Save Sight in Diabetes.

Stanford C Taylor1, Rithwick Rajagopal2.   

Abstract

Owing to the global epidemic of obesity, the incidence of diabetes and its complications are rapidly increasing around the world. Yet, visual impairment caused by diabetic retinopathy is paradoxically on the decline. This improvement is due to better understanding of etiologic mechanisms, increased screening, and advent of newer therapies. Here, we discuss salient developments in the comprehension of the root causes of diabetic retinopathy and the molecular mechanisms underlying current treatment approaches.

Entities:  

Year:  2016        PMID： 30228503      PMCID： PMC6139830     

Source DB:  PubMed          Journal:  Mo Med        ISSN： 0026-6620


  40 in total

Review 1.  Diabetic retinopathy.

Authors:  David A Antonetti; Ronald Klein; Thomas W Gardner
Journal:  N Engl J Med       Date:  2012-03-29       Impact factor: 91.245

2.  Pharmacokinetic rationale for dosing every 2 weeks versus 4 weeks with intravitreal ranibizumab, bevacizumab, and aflibercept (vascular endothelial growth factor Trap-eye).

Authors:  Michael W Stewart; Philip J Rosenfeld; Fernando M Penha; Fenghua Wang; Zohar Yehoshua; Elena Bueno-Lopez; Pedro F Lopez
Journal:  Retina       Date:  2012-03       Impact factor: 4.256

3.  Long-term effects of intensive glucose lowering on cardiovascular outcomes.

Authors:  Hertzel C Gerstein; Michael E Miller; Saul Genuth; Faramarz Ismail-Beigi; John B Buse; David C Goff; Jeffrey L Probstfield; William C Cushman; Henry N Ginsberg; J Thomas Bigger; Richard H Grimm; Robert P Byington; Yves D Rosenberg; William T Friedewald
Journal:  N Engl J Med       Date:  2011-03-03       Impact factor: 91.245

4.  Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.

Authors:  Xiaoban Xin; Murilo Rodrigues; Mahaa Umapathi; Fabiana Kashiwabuchi; Tao Ma; Savalan Babapoor-Farrokhran; Shuang Wang; Jiadi Hu; Imran Bhutto; Derek S Welsbie; Elia J Duh; James T Handa; Charles G Eberhart; Gerard Lutty; Gregg L Semenza; Silvia Montaner; Akrit Sodhi
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-19       Impact factor: 11.205

Review 5.  Diabetic retinopathy, superoxide damage and antioxidants.

Authors:  Julia M Santos; Ghulam Mohammad; Qing Zhong; Renu A Kowluru
Journal:  Curr Pharm Biotechnol       Date:  2011-03-01       Impact factor: 2.837

6.  PPARalpha activators inhibit vascular endothelial growth factor receptor-2 expression by repressing Sp1-dependent DNA binding and transactivation.

Authors:  Markus Meissner; Monika Stein; Carmen Urbich; Kerstin Reisinger; Guntram Suske; Bart Staels; Roland Kaufmann; Jens Gille
Journal:  Circ Res       Date:  2003-12-18       Impact factor: 17.367

7.  Targeted deletion of Vegfa in adult mice induces vision loss.

Authors:  Toshihide Kurihara; Peter D Westenskow; Stephen Bravo; Edith Aguilar; Martin Friedlander
Journal:  J Clin Invest       Date:  2012-10-24       Impact factor: 14.808

8.  Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial.

Authors:  A C Keech; P Mitchell; P A Summanen; J O'Day; T M E Davis; M S Moffitt; M-R Taskinen; R J Simes; D Tse; E Williamson; A Merrifield; L T Laatikainen; M C d'Emden; D C Crimet; R L O'Connell; P G Colman
Journal:  Lancet       Date:  2007-11-07       Impact factor: 79.321

9.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.

Authors: 
Journal:  Lancet       Date:  1998-09-12       Impact factor: 79.321

10.  Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders.

Authors:  L P Aiello; R L Avery; P G Arrigg; B A Keyt; H D Jampel; S T Shah; L R Pasquale; H Thieme; M A Iwamoto; J E Park
Journal:  N Engl J Med       Date:  1994-12-01       Impact factor: 91.245
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  1 in total

1.  Weight Reduction as an Adjunctive Management Strategy for Diabetic Retinopathy.

Authors:  Rithwick Rajagopal
Journal:  Mo Med       Date:  2022 Jan-Feb
  1 in total

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