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Literature DB >> 30224409

New therapies to relieve pain: The search for more efficient and safer alternatives to opioid pain killers.

Philip Hunter¹.
1. London, UK.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2018 PMID： 30224409 PMCID： PMC6172456 DOI： 10.15252/embr.201846925

Source DB: PubMed Journal: EMBO Rep ISSN： 1469-221X Impact factor: 8.807

× No keyword cloud information.

8 in total

1. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.

Authors: Mohab M Ibrahim; Amol Patwardhan; Kerry B Gilbraith; Aubin Moutal; Xiaofang Yang; Lindsey A Chew; Tally Largent-Milnes; T Philip Malan; Todd W Vanderah; Frank Porreca; Rajesh Khanna
Journal: Pain Date: 2017-02 Impact factor: 6.961

2. Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.

Authors: Susruta Majumdar; Steven Grinnell; Valerie Le Rouzic; Maxim Burgman; Lisa Polikar; Michael Ansonoff; John Pintar; Ying-Xian Pan; Gavril W Pasternak
Journal: Proc Natl Acad Sci U S A Date: 2011-11-21 Impact factor: 11.205

3. A nontoxic pain killer designed by modeling of pathological receptor conformations.

Authors: V Spahn; G Del Vecchio; D Labuz; A Rodriguez-Gaztelumendi; N Massaly; J Temp; V Durmaz; P Sabri; M Reidelbach; H Machelska; M Weber; C Stein
Journal: Science Date: 2017-03-03 Impact factor: 47.728

4. Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.

Authors: Kenji Hanamura; Halley R Washburn; Sean I Sheffler-Collins; Nan L Xia; Nathan Henderson; Dipti V Tillu; Shayne Hassler; Daniel S Spellman; Guoan Zhang; Thomas A Neubert; Theodore J Price; Matthew B Dalva
Journal: PLoS Biol Date: 2017-07-18 Impact factor: 8.029

1 in total

Review 1. Opioid Receptors in Immune and Glial Cells-Implications for Pain Control.

Authors: Halina Machelska; Melih Ö Celik
Journal: Front Immunol Date: 2020-03-04 Impact factor: 7.561

1 in total

New therapies to relieve pain: The search for more efficient and safer alternatives to opioid pain killers.

1. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.

2. Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.

3. A nontoxic pain killer designed by modeling of pathological receptor conformations.

4. Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.

5. Brain Connectivity Predicts Placebo Response across Chronic Pain Clinical Trials.

6. Trypsin-protease activated receptor-2 signaling contributes to pancreatic cancer pain.

Review 7. Role of the Bone Microenvironment in the Development of Painful Complications of Skeletal Metastases.

8. Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist.

Review 1. Opioid Receptors in Immune and Glial Cells-Implications for Pain Control.