| Literature DB >> 3022377 |
O Heidmann, A Buonanno, B Geoffroy, B Robert, J L Guénet, J P Merlie, J P Changeux.
Abstract
The chromosomal localization of the genes encoding the four subunits of muscle nicotinic receptor was determined by analyzing restriction fragment length polymorphisms between two mouse species Mus musculus domesticus (DBA/2) and Mus spretus (SPE). Analysis of the progeny of the interspecies mouse backcross (DBA/2 X SPE) X DBA/2 showed that the alpha-subunit gene cosegregates with the alpha-cardiac actin gene on chromosome 17, that the beta-subunit gene is located on chromosome 11, and that the gamma- and delta-subunit genes cosegregate and are located on chromosome 1.Entities:
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Year: 1986 PMID： 3022377 DOI： 10.1126/science.3022377
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728