Literature DB >> 30222897

Review and case report demonstrate that spontaneous spinal epidural abscesses are rare but dangerous in childhood.

Anastasia Fotaki1, Maria Anatoliotaki1, Ioanna Tritou2, Aggeliki Tzagaraki1, Maria Kampitaki3, Georgia Vlachaki1.   

Abstract

AIM: A spinal epidural abscess (SEA) is a rare paediatric bacterial infection, with possible devastating neurological sequelae. We explored localisation in the cervical segment, which is unusual, but more dangerous, than other SEAs.
METHODS: We describe 22 cases (12 male) of paediatric SEAs without risk factors: 21 from a literature search from 2000 to 2017 and a 30-month-old boy with a spontaneous cervical SEA due to Group A Streptococcus.
RESULTS: The average age was eight years and the symptoms were mainly fever, back pain and motor deficit, with an aetiological diagnosis in 68%. Methicillin-sensitive Staphylococcus aureus was isolated in six patients, methicillin-resistant Staphylococcus aureus in two, Staphylococcus aureus with unknown susceptibility patterns in three and Group A Streptococcus in four. All patients underwent gadolinium-enhanced magnetic resonance imaging and most abscesses were localised in the thoracic and lumbar areas. More than half (59%) underwent surgery to remove pus and granulation tissue and nine were just treated with antimicrobial therapy for an average of 5.3 weeks. Most patients had good outcomes.
CONCLUSION: SEAs were underestimated in children due to the rarity and spectrum of differential diagnoses. Timely diagnosis, immediate antibiotics, spinal magnetic resonance imaging and prompt neurosurgical consultations were essential for favourable outcomes. ©2018 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

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Keywords:  zzm321990Staphylococcus aureuszzm321990; Group A Streptococcus; Infection; Magnetic resonance imaging; Spinal epidural abscess

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Year:  2018        PMID: 30222897     DOI: 10.1111/apa.14579

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  2 in total

1.  Successful Treatment of Pediatric Holo-Spinal Epidural Abscess With Percutaneous Drainage.

Authors:  Adam A Ammar; Mousa K Hamad; Malik S Obeidallah; Andrew J Kobets; Seon-Kyu Lee; Ira R Abbott
Journal:  Cureus       Date:  2022-05-04

2.  Pediatric Group A streptococcal spinal epidural abscess presenting with recurrent symptoms of viral illness: An operative case report.

Authors:  Khushdeep S Vig; Matthew Amarante; Ian Hutchinson; James Patrick Lawrence
Journal:  N Am Spine Soc J       Date:  2021-05-08
  2 in total

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