Literature DB >> 30222137

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

Anna Sophia McKenney, Allison N Lau, Amritha Varshini Hanasoge Somasundara, Barbara Spitzer, Andrew M Intlekofer, Jihae Ahn, Kaitlyn Shank, Franck T Rapaport, Minal A Patel, Efthymia Papalexi, Alan H Shih, April Chiu, Elizaveta Freinkman, Esra A Akbay, Mya Steadman, Raj Nagaraja, Katharine Yen, Julie Teruya-Feldstein, Kwok-Kin Wong, Raajit Rampal, Matthew G Vander Heiden, Craig B Thompson, Ross L Levine.   

Abstract

Entities:  

Year:  2018        PMID： 30222137      PMCID： PMC6159958          DOI： 10.1172/JCI124920

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  3 in total

1.  JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms.

Authors:  Tata Nageswara Rao; Nils Hansen; Julian Hilfiker; Shivam Rai; Julia-Magdalena Majewska; Danijela Leković; Deniz Gezer; Nicola Andina; Serena Galli; Teresa Cassel; Florian Geier; Julien Delezie; Ronny Nienhold; Hui Hao-Shen; Christian Beisel; Serena Di Palma; Sarah Dimeloe; Jonel Trebicka; Dominik Wolf; Max Gassmann; Teresa W-M Fan; Andrew N Lane; Christoph Handschin; Stefan Dirnhofer; Nicolaus Kröger; Christoph Hess; Thomas Radimerski; Steffen Koschmieder; Vladan P Čokić; Radek C Skoda
Journal:  Blood       Date:  2019-11-21       Impact factor: 22.113

2.  A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN.

Authors:  Wenbin Xiao; Linde A Miles; Robert L Bowman; Vidushi Durani; Helen S Tian; Nicole L DelGaudio; Tanmay Mishra; Menglei Zhu; Yanming Zhang; Sarah E Stump; Martin S Tallman; Ross L Levine; Sheng F Cai
Journal:  Blood Adv       Date:  2020-12-08

Review 3.  The Molecular Genetics of Myeloproliferative Neoplasms.

Authors:  Anna E Marneth; Ann Mullally
Journal:  Cold Spring Harb Perspect Med       Date:  2020-02-03       Impact factor: 6.915
  3 in total

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