Literature DB >> 30221146

The Management of Inflammatory Bowel Disease in Elderly: Current Evidence and Future Perspectives.

Ian Arnott1, Gerhard Rogler2, Jonas Halfvarson3.   

Abstract

Data on the elderly population with inflammatory bowel disease (IBD) are scarce, as this population is normally excluded from clinical trials. With an ageing population and an overall increasing prevalence of IBD; the incidence of IBD in elderly is rising. Comorbidities, wide differential diagnosis and polypharmacy make the diagnosis and management of the disease in elderly more challenging compared to that in younger adults. The knowledge of specific requirements for the management and treatment of IBD in advanced age may help in the framing of the definition of the appropriate care of this patient group. This manuscript reviews the most recent knowledge in the epidemiology, diagnosis and management of IBD in this population.

Entities:  

Keywords:  Comorbidities; Crohn's disease; Elderly; Management of the disease; Ulcerative colitis

Year:  2018        PMID: 30221146      PMCID: PMC6135226          DOI: 10.1159/000490053

Source DB:  PubMed          Journal:  Inflamm Intest Dis        ISSN: 2296-9365


  48 in total

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Authors:  A Dignass; G Van Assche; J O Lindsay; M Lémann; J Söderholm; J F Colombel; S Danese; A D'Hoore; M Gassull; F Gomollón; D W Hommes; P Michetti; C O'Morain; T Oresland; A Windsor; E F Stange; S P L Travis
Journal:  J Crohns Colitis       Date:  2010-01-15       Impact factor: 9.071

Review 2.  Toxic megacolon.

Authors:  Daniel M Autenrieth; Daniel C Baumgart
Journal:  Inflamm Bowel Dis       Date:  2012-03       Impact factor: 5.325

3.  Risk of comorbidities on postoperative outcomes in patients with inflammatory bowel disease.

Authors:  Gilaad G Kaplan; James Hubbard; Remo Panaccione; Abdel Aziz M Shaheen; Hude Quan; Geoffrey C Nguyen; Elijah Dixon; Subrata Ghosh; Robert P Myers
Journal:  Arch Surg       Date:  2011-08

4.  European Crohn's and Colitis Organisation Topical Review on IBD in the Elderly.

Authors:  Andreas Sturm; Christian Maaser; Michael Mendall; Dimitrios Karagiannis; Pantelis Karatzas; Nienke Ipenburg; Shaji Sebastian; Fernando Rizzello; Jimmy Limdi; Konstantinos Katsanos; Carsten Schmidt; Steven Jeuring; Francesco Colombo; Paolo Gionchetti
Journal:  J Crohns Colitis       Date:  2016-10-20       Impact factor: 9.071

Review 5.  Inflammatory bowel disease in the elderly.

Authors:  Syed Wasif Hussain; Darrell S Pardi
Journal:  Drugs Aging       Date:  2010-08-01       Impact factor: 3.923

6.  Inflammatory bowel disease of the elderly: a wake-up call.

Authors:  Seymour Katz; Richard Feldstein
Journal:  Gastroenterol Hepatol (N Y)       Date:  2008-05

7.  Fecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis than the Lichtiger Index, C-reactive protein, platelets, hemoglobin, and blood leukocytes.

Authors:  Alain M Schoepfer; Christoph Beglinger; Alex Straumann; Ekaterina Safroneeva; Yvonne Romero; David Armstrong; Carsten Schmidt; Michael Trummler; Valérie Pittet; Stephan R Vavricka
Journal:  Inflamm Bowel Dis       Date:  2013-02       Impact factor: 5.325

8.  National differences in ulcerative colitis experience and management among patients from five European countries and Canada: an online survey.

Authors:  Stefan Schreiber; Julián Panés; Edouard Louis; Derek Holley; Mandy Buch; Kristine Paridaens
Journal:  J Crohns Colitis       Date:  2012-08-23       Impact factor: 9.071

Review 9.  Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.

Authors:  L Peyrin-Biroulet; W Sandborn; B E Sands; W Reinisch; W Bemelman; R V Bryant; G D'Haens; I Dotan; M Dubinsky; B Feagan; G Fiorino; R Gearry; S Krishnareddy; P L Lakatos; E V Loftus; P Marteau; P Munkholm; T B Murdoch; I Ordás; R Panaccione; R H Riddell; J Ruel; D T Rubin; M Samaan; C A Siegel; M S Silverberg; J Stoker; S Schreiber; S Travis; G Van Assche; S Danese; J Panes; G Bouguen; S O'Donnell; B Pariente; S Winer; S Hanauer; J-F Colombel
Journal:  Am J Gastroenterol       Date:  2015-08-25       Impact factor: 10.864

10.  Impact of Diagnostic Delay and Associated Factors on Clinical Outcomes in a U.S. Inflammatory Bowel Disease Cohort.

Authors:  Vu Q Nguyen; Dingfeng Jiang; Sharon N Hoffman; Srikar Guntaka; Jessica L Mays; Anthony Wang; Joseph Gomes; Dario Sorrentino
Journal:  Inflamm Bowel Dis       Date:  2017-10       Impact factor: 5.325

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  4 in total

Review 1.  Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management.

Authors:  G Pellino; D S Keller; G M Sampietro; V Annese; M Carvello; V Celentano; C Coco; F Colombo; N Cracco; F Di Candido; M Franceschi; S Laureti; G Mattioli; L Pio; G Sciaudone; G Sica; V Villanacci; R Zinicola; S Leone; S Danese; A Spinelli; G Delaini; F Selvaggi
Journal:  Tech Coloproctol       Date:  2020-01-25       Impact factor: 3.781

Review 2.  (Patho-)Physiology of Na+/H+ Exchangers (NHEs) in the Digestive System.

Authors:  Li Cao; Zhenglin Yuan; Mei Liu; Christian Stock
Journal:  Front Physiol       Date:  2020-01-15       Impact factor: 4.566

3.  Ameliorative effect of galantamine on acetic acid-induced colitis in rats.

Authors:  Niloofar-Sadat Mahdavi; Ardeshir Talebi; Mohsen Minaiyan
Journal:  Res Pharm Sci       Date:  2019-10-04

4.  Elderly-onset vs adult-onset ulcerative colitis: a different natural history?

Authors:  Irene Zammarchi; Francesco Lanzarotto; Rosanna Cannatelli; Francesca Munari; Federica Benini; Alessandro Pozzi; Alberto Lanzini; Chiara Ricci
Journal:  BMC Gastroenterol       Date:  2020-05-12       Impact factor: 3.067

  4 in total

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