Literature DB >> 30220614

Sorting Out the Best: Enriching Hematopoietic Stem Cells for Gene Therapy and Editing.

Stefan Radtke1, Olivier Humbert1, Hans-Peter Kiem2.   

Abstract

Mesh:

Year:  2018        PMID: 30220614      PMCID: PMC6171164          DOI: 10.1016/j.ymthe.2018.08.025

Source DB:  PubMed          Journal:  Mol Ther        ISSN: 1525-0016            Impact factor:   11.454


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  4 in total

1.  Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells.

Authors:  Katelyn E Masiuk; Devin Brown; Jennifer Laborada; Roger P Hollis; Fabrizia Urbinati; Donald B Kohn
Journal:  Mol Ther       Date:  2017-06-27       Impact factor: 11.454

2.  A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.

Authors:  Stefan Radtke; Jennifer E Adair; Morgan A Giese; Yan-Yi Chan; Zachary K Norgaard; Mark Enstrom; Kevin G Haworth; Lauren E Schefter; Hans-Peter Kiem
Journal:  Sci Transl Med       Date:  2017-11-01       Impact factor: 17.956

3.  Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.

Authors:  Jennifer E Adair; Timothy Waters; Kevin G Haworth; Sara P Kubek; Grant D Trobridge; Jonah D Hocum; Shelly Heimfeld; Hans-Peter Kiem
Journal:  Nat Commun       Date:  2016-10-20       Impact factor: 14.919

4.  Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy.

Authors:  Erika Zonari; Giacomo Desantis; Carolina Petrillo; Francesco E Boccalatte; Maria Rosa Lidonnici; Anna Kajaste-Rudnitski; Alessandro Aiuti; Giuliana Ferrari; Luigi Naldini; Bernhard Gentner
Journal:  Stem Cell Reports       Date:  2017-03-16       Impact factor: 7.765

  4 in total
  2 in total

Review 1.  Mouse models in hematopoietic stem cell gene therapy and genome editing.

Authors:  Stefan Radtke; Olivier Humbert; Hans-Peter Kiem
Journal:  Biochem Pharmacol       Date:  2019-11-06       Impact factor: 5.858

2.  Isolation of a Highly Purified HSC-enriched CD34+CD90+CD45RA- Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model.

Authors:  Stefan Radtke; Lucrezia Colonna; Anai M Perez; Michelle Hoffman; Leslie S Kean; Hans-Peter Kiem
Journal:  Transplant Direct       Date:  2020-07-15
  2 in total

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