Literature DB >> 30220553

Atypical Protein Kinase C: Breaking Down Barriers in Ocular Disease?

Elizabeth A Pearsall1, Kip M Connor2.   

Abstract

This commentary highlights the article by Lin et al that demonstrates the therapeutic potential of small-molecule atypical protein kinase C inhibitors in inflammatory ocular disease.
Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30220553      PMCID： PMC6180271          DOI： 10.1016/j.ajpath.2018.07.006

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


  23 in total

Review 1.  Diabetic retinopathy.

Authors:  David A Antonetti; Ronald Klein; Thomas W Gardner
Journal:  N Engl J Med       Date:  2012-03-29       Impact factor: 91.245

Review 2.  The inner blood-retinal barrier: Cellular basis and development.

Authors:  Mónica Díaz-Coránguez; Carla Ramos; David A Antonetti
Journal:  Vision Res       Date:  2017-06-27       Impact factor: 1.886

3.  TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis.

Authors:  Hu Huang; Jarel K Gandhi; Xiufeng Zhong; Yanhong Wei; Junsong Gong; Elia J Duh; Stanley A Vinores
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-03-10       Impact factor: 4.799

Review 4.  Anti-vascular endothelial growth factor treatment for retinal vein occlusions.

Authors:  Peter A Campochiaro
Journal:  Ophthalmologica       Date:  2012-04-24       Impact factor: 3.250

5.  Intravitreal infliximab in patients with macular degeneration who are nonresponders to antivascular endothelial growth factor therapy.

Authors:  Luis Arias; Jose M Caminal; Maria B Badia; Marcos J Rubio; Jaume Catala; Octavio Pujol
Journal:  Retina       Date:  2010 Nov-Dec       Impact factor: 4.256

6.  Suppression of protein kinase C-ζ attenuates vascular leakage via prevention of tight junction protein decrease in diabetic retinopathy.

Authors:  Hyun Beom Song; Hyoung-Oh Jun; Jin Hyoung Kim; Young Suk Yu; Kyu Won Kim; Jeong Hun Kim
Journal:  Biochem Biophys Res Commun       Date:  2014-01-14       Impact factor: 3.575

Review 7.  Protein kinase C: poised to signal.

Authors:  Alexandra C Newton
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-11-24       Impact factor: 4.310

8.  The activation of the atypical PKC zeta in light-induced retinal degeneration and its involvement in L-DNase II control.

Authors:  Imene Jaadane; Sabine Chahory; Chloé Leprêtre; Boubaker Omri; Laurent Jonet; Francine Behar-Cohen; Patricia Crisanti; Alicia Torriglia
Journal:  J Cell Mol Med       Date:  2015-03-17       Impact factor: 5.310

9.  Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment.

Authors:  Yoko Okunuki; Ryo Mukai; Elizabeth A Pearsall; Garrett Klokman; Deeba Husain; Dong-Ho Park; Ekaterina Korobkina; Howard L Weiner; Oleg Butovsky; Bruce R Ksander; Joan W Miller; Kip M Connor
Journal:  Proc Natl Acad Sci U S A       Date:  2018-06-18       Impact factor: 11.205

10.  PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation.

Authors:  Dinusha Rajapakse; Mei Chen; Tim M Curtis; Heping Xu
Journal:  Aging (Albany NY)       Date:  2017-10-09       Impact factor: 5.682
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