| Literature DB >> 30220435 |
J D Pallua1, A Brunner2, B Zelger2, R Stalder3, S H Unterberger4, M Schirmer5, M C Tappert6.
Abstract
New developments in Mid-infrared microscopic imaging instrumentation and data analysis have turned this method into a conventional technique. This imaging method offers a global analysis of samples, with a resolution close to the cellular level enabling the acquisition of local molecular expression profiles. It is possible to get chemo-morphological information about the tissue status, which represents an essential benefit for future analytical interpretation of pathological changes of tissue. In this review, we give an overview of Mid-infrared microscopic imaging and its applications in clinical research.Keywords: Chemical as well as physical sample properties; Histopathology; Mid-infrared microscopic imaging; Molecular fingerprint; Statistical classification; Three-dimensional image data cube
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Year: 2018 PMID： 30220435 DOI： 10.1016/j.prp.2018.08.026
Source DB: PubMed Journal: Pathol Res Pract ISSN： 0344-0338 Impact factor: 3.250