| Literature DB >> 30219743 |
Emilie Lommers1, Frédérique Depierreux2, Isabelle Hansen3, Dominique Dive3, Pierre Maquet3.
Abstract
Tumor necrosis factor α (TNFα) inhibitors are highly effective and a therapeutic choice for several inflammatory diseases. Their broad and long-term use is associated with a growing number of paradoxical autoimmune events including demyelinating lesions of the central nervous system (CNS). We report and discuss a case of neuromyelitis optica spectrum disorder (NMOSD) with positive myelin oligodendrocyte glycoprotein antibodies (MOG-IgG1) following anti-TNFα therapy for a pustular psoriasis.Entities:
Keywords: Demyelinating lesions; MOG-IgG; NMOSD; TNFα blockers
Mesh:
Substances:
Year: 2018 PMID: 30219743 DOI: 10.1016/j.msard.2018.08.029
Source DB: PubMed Journal: Mult Scler Relat Disord ISSN: 2211-0348 Impact factor: 4.339