| Literature DB >> 30219321 |
Sarah S Cherian1, A M Walimbe2, Karan Moolpani2, Amruta Shirode2, Sunil R Vaidya2.
Abstract
Measles viruses (MeV) circulating in India mainly belong to genoypes D4 and D8 of clade D. In the context of measles elimination goal 2020 in India, molecular clock and phylogeography studies would help to identify the timescales of evolution and track the transmission pathways of MeV. We used nucleoprotein gene sequences (n = 756) from GenBank, representing 86 countries (1973-2016), to study the spatiotemporal transmission dynamics of clade D. Genotype D4 was introduced into India around 1991 and genotype D8 around 1994. Recent transmissions of the D4 genotype of measles virus (MeV) were noted from India to the United States of America and East Asia region while D8 genotype importations from North America were noted in recent years.Entities:
Keywords: Clade D; Genotype D4; Genotype D8; Global phylogeography; India; Measles virus
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Year: 2018 PMID： 30219321 DOI： 10.1016/j.meegid.2018.09.007
Source DB: PubMed Journal: Infect Genet Evol ISSN： 1567-1348 Impact factor: 3.342