| Literature DB >> 30219184 |
Hojjat Ahmadzadehfar1, Markus Essler2, Kambiz Rahbar3, Ali Afshar-Oromieh4.
Abstract
The skeleton is a common site for cancer metastases. Bone metastases are a major cause of morbidity and mortality and associated with pain, pathologic fractures, spinal cord compression, and decreased survival. Various radionuclides have been used for pain therapy. Recently, an α-emitter has been shown to improve overall survival of patients with bone metastases from castration-resistant prostate cancer and was approved as a therapeutic agent. The aim of this article is to provide an overview regarding state of the art radionuclide therapy options for bone metastases, with focus on the role of PET imaging in therapy planning.Entities:
Keywords: Bone metastases; Breast cancer; Lung cancer; PET; Prostate cancer; Radionuclide therapy; Radium-223
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Year: 2018 PMID: 30219184 DOI: 10.1016/j.cpet.2018.05.005
Source DB: PubMed Journal: PET Clin ISSN: 1556-8598