Literature DB >> 30217780

Alignment Risk Factors for Proximal Junctional Kyphosis and the Effect of Lower Thoracic Junctional Tethers for Adult Spinal Deformity.

Thomas J Buell1, Ching-Jen Chen2, John C Quinn3, Avery L Buchholz4, Marcus D Mazur2, Jeffrey P Mullin2, James H Nguyen2, Davis G Taylor2, Shay Bess5, Breton G Line5, Christopher P Ames6, Frank J Schwab7, Virginie Lafage7, Christopher I Shaffrey2, Justin S Smith2.   

Abstract

OBJECTIVE: The aims of this retrospective cohort study were to 1) identify new alignment risk factors for proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) patients with lower thoracic upper instrumented vertebra (UIV) and 2) determine the effect of junctional tethers on PJK and UIV alignment.
METHODS: We analyzed consecutive ASD patients who underwent posterior instrumented fusion with lower thoracic UIV (T9-T11). Posteriorly anchored junctional tethers were used more recently for ligamentous augmentation to prevent PJK. In addition to regional and global parameters, upper segmental lumbar lordosis (ULL) versus lower segmental lumbar lordosis and UIV angle (measured from UIV inferior endplate to horizontal) were assessed. Primary outcome of PJK was defined as proximal junctional angle >10° and >10° greater than the corresponding preoperative measurement. Univariable and multivariable analyses were performed.
RESULTS: The study cohort comprised 120 ASD patients (mean age, 67 years) with minimum 1-year follow-up. Preoperative ULL (P = 0.034) and UIV angle (P = 0.026) were associated with PJK. No independent preoperative alignment risk factors of PJK were identified in multivariable analysis. Tether use was protective against PJK (odds ratio, 0.063 [0.016-0.247]; P < 0.001). PJK in tethered patients was more common with greater postoperative ULL (P = 0.047) and UIV angle (P = 0.026).
CONCLUSIONS: Junctional tethers significantly reduced PJK in ASD patients with lower thoracic UIV. In tethered patients, PJK was more common with greater postoperative lordosis of the upper lumbar spine and greater UIV angle. This finding suggests potential benefit of tethers to mitigate effects of segmental lumbar and focal UIV malalignment that may occur after deformity surgery.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adjacent segment disease; Adult spinal deformity; Complication; Proximal junctional kyphosis; Scoliosis; Spinal fusion; Tethers

Mesh:

Year:  2018        PMID: 30217780     DOI: 10.1016/j.wneu.2018.08.242

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  9 in total

Review 1.  Incidence and risk factors of proximal junctional kyphosis after internal fixation for adult spinal deformity: a systematic evaluation and meta-analysis.

Authors:  Jian Zhao; Kai Chen; Xiao Zhai; Kai Chen; Ming Li; Yanghu Lu
Journal:  Neurosurg Rev       Date:  2020-05-19       Impact factor: 3.042

2.  Posterior Ligamentous Reinforcement of the Upper Instrumented Vertebrae +1 Does Not Decrease Proximal Junctional Kyphosis in Adult Spinal Deformity.

Authors:  Sravisht Iyer; Francis Lovecchio; Jonathan Charles Elysée; Renaud Lafage; Michael Steinhaus; Frank J Schwab; Virginie Lafage; Han Jo Kim
Journal:  Global Spine J       Date:  2019-08-15

3.  Prediction of Proximal Junctional Kyphosis After Posterior Scoliosis Surgery With Machine Learning in the Lenke 5 Adolescent Idiopathic Scoliosis Patient.

Authors:  Li Peng; Lan Lan; Peng Xiu; Guangming Zhang; Bowen Hu; Xi Yang; Yueming Song; Xiaoyan Yang; Yonghong Gu; Rui Yang; Xiaobo Zhou
Journal:  Front Bioeng Biotechnol       Date:  2020-10-06

4.  Degenerative lumbar scoliosis patients with proximal junctional kyphosis have lower muscularity, fatty degeneration at the lumbar area.

Authors:  Lei Yuan; Yan Zeng; Zhongqiang Chen; Weishi Li; Xinling Zhang; Shuo Mai
Journal:  Eur Spine J       Date:  2020-11-19       Impact factor: 3.134

5.  Radiographic outcomes and complications after L4 or L5 pedicle subtraction osteotomy for fixed sagittal malalignment in 102 adult spinal deformity patients with a minimum 2-year follow-up.

Authors:  Anouar Bourghli; Louis Boissiere; Thomas Chevillotte; Maxime Huneidi; Clement Silvestre; Kariman Abelin-Genevois; Pierre Grobost; Javier Pizones; Pierre Roussouly; Ibrahim Obeid
Journal:  Eur Spine J       Date:  2021-09-29       Impact factor: 3.134

Review 6.  State of the art: proximal junctional kyphosis-diagnosis, management and prevention.

Authors:  Zeeshan M Sardar; Yongjung Kim; Virginie Lafage; Frank Rand; Lawrence Lenke; Eric Klineberg
Journal:  Spine Deform       Date:  2021-01-15

7.  Correlation of Acetabular Anteversion and Thoracic Kyphosis Postoperatively with Proximal Junctional Failure in Adult Spinal Deformity Fused to Pelvis.

Authors:  Zi-Fang Zhang; Deng-Bin Qi; Tian-Hao Wang; Zheng Wang; Guo-Quan Zheng; Yan Wang
Journal:  Orthop Surg       Date:  2021-10-27       Impact factor: 2.071

8.  A Review of Strategies to Improve Biomechanical Fixation in the Cervical Spine.

Authors:  Colby Oitment; Patrick Thornley; Frank Koziarz; Thorsten Jentzsch; Kunal Bhanot
Journal:  Global Spine J       Date:  2022-01-12

9.  Instrumentation Techniques to Prevent Proximal Junctional Kyphosis and Proximal Junctional Failure in Adult Spinal Deformity Correction: A Systematic Review of Clinical Studies.

Authors:  Timon F G Vercoulen; Remco J P Doodkorte; Alex Roth; Rob de Bie; Paul C Willems
Journal:  Global Spine J       Date:  2021-07-30
  9 in total

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