Literature DB >> 30217130

Primary surgical repair of tetralogy of Fallot at under three months of age.

Andrew B Ho1, Tara Bharucha1, Eleanor Jones2, Justin Thuraisingham1, Markku Kaarne3, Nicola Viola3.   

Abstract

Background Classical management of small infants with tetralogy of Fallot has involved placement of a Blalock-Taussig shunt followed later by complete repair, rather than primary complete repair which is the strategy adopted in larger infants. Some advantages of early complete repair compared to a staged strategy have been shown. We sought to review our institutional outcomes. Methods Patients under 3-months old undergoing complete surgical repair of tetralogy of Fallot in our institution between 2005 and 2015 were retrospectively reviewed and compared with an older control group matched by anatomical diagnosis and outflow tract intervention. Results Fourteen index cases (group A) and 14 controls (group B) were identified. At surgery, the median age was 43 days and weight 4.2 kg in group A, and 130 days and 6.1 kg in group B. Nine of 14 in group A were admitted for surgery as emergencies compared to none in group B. Peak inotrope score (22.3 vs. 12.8, p = 0.02) and intensive care unit stay (4.4 vs. 2.6 days, p = 0.02) were higher in group A. Bypass and crossclamp times, duration of intubation, and total length of stay did not differ. Conclusions We conclude that although babies undergoing early repair of tetralogy of Fallot have an increased need for intensive care support in the early postoperative period, the total length of stay is not prolonged despite more emergency admissions. As it is known that early repair may reduce long-term morbidity, we propose consideration of earlier complete repair of tetralogy of Fallot.

Entities:  

Keywords:  Age factors; Cardiac surgical procedures; Infant; Intensive care units; Tetralogy of Fallot; Treatment outcome.; pediatric

Mesh:

Year:  2018        PMID: 30217130     DOI: 10.1177/0218492318803037

Source DB:  PubMed          Journal:  Asian Cardiovasc Thorac Ann        ISSN: 0218-4923


  3 in total

1.  The Limited Benefit of Follow-Up Echocardiograms After Repair of Tetralogy of Fallot.

Authors:  Jack Xu; Caleb Guthrey; Stephen Dalby; Xinyu Tang; Joshua Daily; R Thomas Collins
Journal:  Pediatr Cardiol       Date:  2019-09-18       Impact factor: 1.655

2.  Conal Septal Hypoplasia in Tetralogy of Fallot-Impact on Clinical Course, Treatment Strategies, and Outcomes After Surgical Intervention.

Authors:  Kirsten E Borsheim; Ronald K Woods; Evelyn M Kuhn; Peter C Frommelt
Journal:  Pediatr Cardiol       Date:  2022-07-19       Impact factor: 1.838

3.  The Effect of Abnormal Regional Homogeneity and Spontaneous Low-Frequency Brain Activity on Lower Cognitive Ability: A Cross-Sectional Study on Postoperative Children With Tetralogy of Fallot.

Authors:  Siyu Ma; Yuanli Hu; Yuting Liu; Yiwei Pu; Pengcheng Zuo; Qinghui Hu; Zhaocong Yang; Feng Chen; Zongyun Xie; Yueshuang Cun; Xiaoxu Liu; Ming Yang; Xuming Mo
Journal:  Front Neurosci       Date:  2022-02-07       Impact factor: 4.677

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.