Literature DB >> 302163

Alpha-I-antitrypsin (Pi) phenotypes in Lyon, France: departure from Hardy-Weinberg equilibrium.

P Arnaud, J P Pandey, H H Fudenberg, C Chapuis-Cellier, P Vittoz, R Creyssel.   

Abstract

The validity of the Hardy-Weinberg equilibrium for Pi phenotypes was tested in a population of 1,653 randomly selected, healthy blood donors in Lyon, France. A significant departure from the equilibrium was found, with an excess of FF and SS homozygotes and a deficiency of FM heterozygotes.

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Year:  1977        PMID: 302163     DOI: 10.1111/j.1399-0004.1977.tb00905.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN: 0009-9163            Impact factor:   4.438


  1 in total

1.  A new allele of human alpha1-antitrypsin: PiNhampton.

Authors:  P Arnaud; R M Galbraith; G M Galbraith; R C Allen; H H Fudenberg
Journal:  Am J Hum Genet       Date:  1978-11       Impact factor: 11.025

  1 in total

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