Literature DB >> 3021530

Specific effects of ATP on the kinetics of reconstituted bovine heart cytochrome-c oxidase.

F J Hüther, B Kadenbach.   

Abstract

Bovine heart cytochrome-c oxidase was reconstituted in liposomes and the kinetics of cytochrome c oxidation were measured by the polarographic and photometric method under uncoupled conditions in the presence of various polyvalent anions. In order to distinguish between specific and unspecific ionic effects of ATP, the photolabelling reagent 8-azido-ATP was applied. Covalently bound ATP at the enzyme complex caused the same increase of Km for cytochrome c as free ATP, if measured by the photometric assay. The increase of Km by photolabelling with 8-azido-ATP was completely prevented by ATP, but not by ADP. The data indicate the occurrence of a specific binding site for ATP at the cytosolic side of cytochrome-c oxidase, which, after binding of ATP, changes the kinetics of cytochrome c oxidation.

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Year:  1986        PMID： 3021530     DOI： 10.1016/0014-5793(86)80018-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

Review 1.  Evolutionary aspects of cytochrome c oxidase.

Authors:  B Kadenbach; A Stroh; F J Hüther; A Reimann; D Steverding
Journal:  J Bioenerg Biomembr       Date:  1991-04       Impact factor: 2.945

2.  Inhibition of the phosphate-stimulated cytochrome c oxidase activity by thiophosphate.

Authors:  S Manon; N Camougrand; M Guerin
Journal:  J Bioenerg Biomembr       Date:  1989-06       Impact factor: 2.945

Review 3.  Complexity and tissue specificity of the mitochondrial respiratory chain.

Authors:  R A Capaldi; D G Halphen; Y Z Zhang; W Yanamura
Journal:  J Bioenerg Biomembr       Date:  1988-06       Impact factor: 2.945

4.  Anions induce conformational changes and influence the activity and photoaffinity-labelling by 8-azido-ATP of isolated cytochrome c oxidase.

Authors:  A Reimann; F J Hüther; J A Berden; B Kadenbach
Journal:  Biochem J       Date:  1988-09-15       Impact factor: 3.857

5.  Ferricytochrome c induces monophasic kinetics of ferrocytochrome c oxidation in cytochrome c oxidase.

Authors:  A Reimann; K H Röhm; B Kadenbach
Journal:  J Bioenerg Biomembr       Date:  1993-08       Impact factor: 2.945

6.  Tissue-specific regulation of bovine heart cytochrome-c oxidase activity by ADP via interaction with subunit VIa.

Authors:  G Anthony; A Reimann; B Kadenbach
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

7.  ATP binding to cytochrome c diminishes electron flow in the mitochondrial respiratory pathway.

Authors:  D B Craig; C J Wallace
Journal:  Protein Sci       Date:  1993-06       Impact factor: 6.725

8.  Influence of 8-azido-ATP and other anions on the activity of cytochrome c oxidase.

Authors:  F J Hüther; J Berden; B Kadenbach
Journal:  J Bioenerg Biomembr       Date:  1988-08       Impact factor: 2.945

9.  The mechanism for the ATP-induced uncoupling of respiration in mitochondria of the yeast Saccharomyces cerevisiae.

Authors:  S Prieto; F Bouillaud; E Rial
Journal:  Biochem J       Date:  1995-05-01       Impact factor: 3.857

10.  The brown and brite adipocyte marker Cox7a1 is not required for non-shivering thermogenesis in mice.

Authors:  Stefanie F Maurer; Tobias Fromme; Lawrence I Grossman; Maik Hüttemann; Martin Klingenspor
Journal:  Sci Rep       Date:  2015-12-04       Impact factor: 4.379
  10 in total

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