Literature DB >> 30215201

Financial Impact of Anastomotic Leakage in Colorectal Surgery.

Davide La Regina1, Matteo Di Giuseppe1, Massimo Lucchelli2, Andrea Saporito3, Luigi Boni4, Christopher Efthymiou5, Stefano Cafarotti1, Michele Marengo1, Francesco Mongelli6.   

Abstract

BACKGROUND: Anastomotic leakage after colorectal surgery is a complication that requires additional treatments strongly affecting the economic outcomes. We evaluated the use of resources and the economic burden associated with anastomotic leaks following colorectal surgery.
METHODS: Between January 2015 and December 2016, we retrospectively evaluated patients who underwent colorectal surgery with primary anastomosis. We compared the medical resource utilization and the DRG-based reimbursement of cases with uncomplicated surgery and cases complicated by anastomotic leakage.
RESULTS: Of the 95 patients included in the study, 87 (92%) presented an uneventful postoperative course and 8 patients (8%) developed an anastomotic leakage requiring surgery. The statistical analysis showed no significant differences in terms of demographics, risks factor, and operative results, except the length of hospital stay (9.7 vs. 29.1 days, p < 0.01). The cost for 87 uncomplicated cases was 1,535,297 EUR (average cost of 17,647 EUR), whereas the cost of the 8 patients with anastomotic leakage was 575,822 EUR (average cost of 71,978 EUR) (p < 0.01). For each patient, the hospital had 542 EUR profit in the uncomplicated group and a 12,181 EUR loss in the anastomotic leakage group (p < 0.01). The multiple R-squared line regression analysis showed that factors independently related to costs were age (p = 0.05) and length of hospital stay (p = 0.01).
CONCLUSIONS: In terms of economic impact, the occurrence of an anastomotic leakage has a large negative influence on medical resource utilization, so that, despite the complication-related increase of DRG-reimbursement, every complicated case represents a financial burden for the hospital.

Entities:  

Keywords:  Colonic; Complications; Diseases; Economics; Postoperative

Mesh:

Year:  2018        PMID: 30215201     DOI: 10.1007/s11605-018-3954-z

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  12 in total

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Journal:  J Am Coll Surg       Date:  2008-12-04       Impact factor: 6.113

2.  Diagnosis related groups in Europe: moving towards transparency, efficiency, and quality in hospitals?

Authors:  Reinhard Busse; Alexander Geissler; Ain Aaviksoo; Francesc Cots; Unto Häkkinen; Conrad Kobel; Céu Mateus; Zeynep Or; Jacqueline O'Reilly; Lisbeth Serdén; Andrew Street; Siok Swan Tan; Wilm Quentin
Journal:  BMJ       Date:  2013-06-07

3.  The Clavien-Dindo classification of surgical complications: five-year experience.

Authors:  Pierre A Clavien; Jeffrey Barkun; Michelle L de Oliveira; Jean Nicolas Vauthey; Daniel Dindo; Richard D Schulick; Eduardo de Santibañes; Juan Pekolj; Ksenija Slankamenac; Claudio Bassi; Rolf Graf; René Vonlanthen; Robert Padbury; John L Cameron; Masatoshi Makuuchi
Journal:  Ann Surg       Date:  2009-08       Impact factor: 12.969

4.  Hospital payment based on diagnosis-related groups differs in Europe and holds lessons for the United States.

Authors:  Wilm Quentin; David Scheller-Kreinsen; Miriam Blümel; Alexander Geissler; Reinhard Busse
Journal:  Health Aff (Millwood)       Date:  2013-04       Impact factor: 6.301

5.  Colorectal anastomotic leakage: aspects of prevention, detection and treatment.

Authors:  Freek Daams; Misha Luyer; Johan F Lange
Journal:  World J Gastroenterol       Date:  2013-04-21       Impact factor: 5.742

6.  The implementation of DRG-based hospital reimbursement in Switzerland: A population-based perspective.

Authors:  André Busato; Georg von Below
Journal:  Health Res Policy Syst       Date:  2010-10-16

7.  The Dutch surgical colorectal audit.

Authors:  N J Van Leersum; H S Snijders; D Henneman; N E Kolfschoten; G A Gooiker; M G ten Berge; E H Eddes; M W J M Wouters; R A E M Tollenaar; W A Bemelman; R M van Dam; M A Elferink; Th M Karsten; J H J M van Krieken; V E P P Lemmens; H J T Rutten; E R Manusama; C J H van de Velde; W J H J Meijerink; Th Wiggers; E van der Harst; J W T Dekker; D Boerma
Journal:  Eur J Surg Oncol       Date:  2013-07-18       Impact factor: 4.424

8.  The impact of complications following open colectomy on hospital finances: a retrospective cohort study.

Authors:  David N Flynn; Rebecca M Speck; Najjia N Mahmoud; Guy David; Lee A Fleisher
Journal:  Perioper Med (Lond)       Date:  2014-03-07

9.  The burden of gastrointestinal anastomotic leaks: an evaluation of clinical and economic outcomes.

Authors:  Jeffrey Hammond; Sangtaeck Lim; Yin Wan; Xin Gao; Anuprita Patkar
Journal:  J Gastrointest Surg       Date:  2014-06       Impact factor: 3.452

10.  Incidence and costs of bleeding-related complications in French hospitals following surgery for various diagnoses.

Authors:  Xin Ye; Antoine Lafuma; Elodie Torreton; Axel Arnaud
Journal:  BMC Health Serv Res       Date:  2013-05-22       Impact factor: 2.655

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  12 in total

Review 1.  Assessment of intraoperative use of indocyanine green fluorescence imaging on the incidence of anastomotic leakage after rectal cancer surgery: a PRISMA-compliant systematic review and meta-analysis.

Authors:  M Song; J Liu; D Xia; H Yao; G Tian; X Chen; Y Liu; Y Jiang; Z Li
Journal:  Tech Coloproctol       Date:  2020-09-03       Impact factor: 3.781

2.  Opioid-Free Anesthesia in Bariatric Surgery: a Propensity Score-Matched Analysis.

Authors:  Alessandro Torre; Michele Marengo; Nicola S Ledingham; Costanza Ajani; Francesco Volontè; Fabio Garofalo; Francesco Mongelli
Journal:  Obes Surg       Date:  2022-03-16       Impact factor: 3.479

3.  Preoperative biomarkers related to inflammation may identify high-risk anastomoses in colorectal cancer surgery: explorative study.

Authors:  Klas Holmgren; Pär Jonsson; Christina Lundin; Peter Matthiessen; Jörgen Rutegård; Malin Sund; Martin Rutegård
Journal:  BJS Open       Date:  2022-05-02

4.  Impact of the novel powered circular stapler on risk of anastomotic leakage in colorectal anastomosis: a propensity score-matched study.

Authors:  V Pla-Martí; J Martín-Arévalo; D Moro-Valdezate; S García-Botello; I Mora-Oliver; R Gadea-Mateo; C Cozar-Lozano; A Espí-Macías
Journal:  Tech Coloproctol       Date:  2020-09-10       Impact factor: 3.781

5.  Ultrasound-Guided Pudendal Nerve Block in Patients Undergoing Open Hemorrhoidectomy: A Post-Hoc Cost-Effectiveness Analysis from a Double-Blind Randomized Controlled Trial.

Authors:  Francesco Mongelli; Massimo Lucchelli; Davide La Regina; Dimitri Christoforidis; Andrea Saporito; Alberto Vannelli; Matteo Di Giuseppe
Journal:  Clinicoecon Outcomes Res       Date:  2021-04-28

6.  Use of near-infrared imaging using indocyanine green associates with the lower incidence of postoperative complications for intestinal and mesenteric injury.

Authors:  Keishi Yamaguchi; Takeru Abe; Kento Nakajima; Chikara Watanabe; Yusuke Kawamura; Hirokazu Suwa; Yuta Minami; Kazunori Nojiri; Hidetaka Ono; Kenichi Yoshida; Hidenobu Masui; Tomoki Doi; Ichiro Takeuchi
Journal:  Sci Rep       Date:  2021-12-13       Impact factor: 4.379

7.  Clinical impact of the triple-layered circular stapler for reducing the anastomotic leakage in rectal cancer surgery: Porcine model and multicenter retrospective cohort analysis.

Authors:  Ryota Nakanishi; Yoshiaki Fujimoto; Masahiko Sugiyama; Yuichi Hisamatsu; Tomonori Nakanoko; Koji Ando; Mitsuhiko Ota; Yasue Kimura; Eiji Oki; Tomoharu Yoshizumi
Journal:  Ann Gastroenterol Surg       Date:  2021-10-07

8.  Mesenteric occlusive disease of the inferior mesenteric artery is associated with anastomotic leak after left-sided colon and rectal cancer surgery: a retrospective cohort study.

Authors:  Melissa N N Arron; Richard P G Ten Broek; Carleen M E M Adriaansens; Stijn Bluiminck; Bob J van Wely; Floris T J Ferenschild; Henk F M Smits; Harry van Goor; Johannes H W de Wilt; André S van Petersen
Journal:  Int J Colorectal Dis       Date:  2022-01-07       Impact factor: 2.571

Review 9.  Predictive and Diagnostic Biomarkers of Anastomotic Leakage: A Precision Medicine Approach for Colorectal Cancer Patients.

Authors:  Mark Gray; Jamie R K Marland; Alan F Murray; David J Argyle; Mark A Potter
Journal:  J Pers Med       Date:  2021-05-25

10.  Novel nomogram for predicting risk of early postoperative small bowel obstruction after right colectomy for cancer.

Authors:  Huida Zheng; Yurong Liu; Zhenze Chen; Yafeng Sun; Jianhua Xu
Journal:  World J Surg Oncol       Date:  2022-01-21       Impact factor: 3.253

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