Mehdi Fathi1, Amin Azhari2, Amir Zanguee2, Mitra Joudi3, Farideh Jamali-Behnam4, Behrooz Mohammadipanah5, Javad Mirzapour5, Ali Vahidirad5, Seyedeh Golnaz Seyedin-Ghannad5, Marjan Joudi4,6. 1. Mashhad University of Medical Sciences, Mashhad, Iran. 2. School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. 3. Department of Psychiatry, School of Medicine, Gorgan University of Medical Sciences, Gorgan, Iran. 4. Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. 5. Department of General Surgery, Mashhad University of Medical Sciences, Mashhad, Iran. 6. Department of Pediatric Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract
BACKGROUND: Hypnosis is a psychological method used for treatment of different types of disorders and illnesses. This technique is also used in surgical interventions. Many studies proved the efficacy of hypnosis in medical treatment. However, the mechanism of hypnosis is unclear for scientists. To find out if the peripheral nervous system has a role in hypnotic anesthesia, we aimed to investigate the effect of hypnotic anesthesia on nerve conduction velocity (NCV). METHODS: In this study, healthy volunteers with high hypnotizability entered the study. First, The NCV test was performed in both hands of participants and then they all underwent hypnosis. Hypnotic anesthesia was induced in the right hand of all subjects followed by painful stimuli in their hand by vascular clasping. Then, the NCV test was repeated in both hands again. Data were analyzed by SPSS version16. RESULTS: The group study consisted of 13 (65%) women and 7 (35%) men with their age ranging between 14 to 52 years. According to the results, the mean values of sensory latency, and NCV changed from 3.225 ms and 54.355 m/s before hypnotic anesthesia to 3.32 ms and 55.3 m/s after hypnotic anesthesia in right hand, respectively. Results showed that there was a significant difference between data before and after hypnotic induction (P < 0.001). The covariance test also indicated a significant difference between the data obtained from both hands (P < 0.001). CONCLUSIONS: In contrast to our hypothesis, the NCV test showed an increase after the hypnotic anesthesia. However, increase in NCV did not lead to experience pain after the painful stimuli. It seems that central nervous system should be involved in this process.
BACKGROUND: Hypnosis is a psychological method used for treatment of different types of disorders and illnesses. This technique is also used in surgical interventions. Many studies proved the efficacy of hypnosis in medical treatment. However, the mechanism of hypnosis is unclear for scientists. To find out if the peripheral nervous system has a role in hypnotic anesthesia, we aimed to investigate the effect of hypnotic anesthesia on nerve conduction velocity (NCV). METHODS: In this study, healthy volunteers with high hypnotizability entered the study. First, The NCV test was performed in both hands of participants and then they all underwent hypnosis. Hypnotic anesthesia was induced in the right hand of all subjects followed by painful stimuli in their hand by vascular clasping. Then, the NCV test was repeated in both hands again. Data were analyzed by SPSS version16. RESULTS: The group study consisted of 13 (65%) women and 7 (35%) men with their age ranging between 14 to 52 years. According to the results, the mean values of sensory latency, and NCV changed from 3.225 ms and 54.355 m/s before hypnotic anesthesia to 3.32 ms and 55.3 m/s after hypnotic anesthesia in right hand, respectively. Results showed that there was a significant difference between data before and after hypnotic induction (P < 0.001). The covariance test also indicated a significant difference between the data obtained from both hands (P < 0.001). CONCLUSIONS: In contrast to our hypothesis, the NCV test showed an increase after the hypnotic anesthesia. However, increase in NCV did not lead to experience pain after the painful stimuli. It seems that central nervous system should be involved in this process.