Literature DB >> 30213217

Implementation of a Direct Oral Anticoagulation Screening Service at a Large Academic Medical Center Provided by a Pharmacist-managed Antithrombosis Clinic as a Method to Expand Antithrombotic Stewardship Efforts.

Ellen M Uppuluri1, Meghan N McComb1, Nancy L Shapiro1.   

Abstract

BACKGROUND: How and when to monitor direct oral anticoagulants (DOACs) for safety and efficacy is a question many anticoagulation clinics are trying to answer. A pharmacist-led antithrombosis clinic (ATC) initiated a clinical service to provide oversight for all prescribed DOACs.
OBJECTIVE: Describe the implementation and outcomes of a DOAC screening service.
METHODS: The service was initiated utilizing a daily electronic prescribing report of DOAC prescriptions. Prescriptions were reviewed by clinical pharmacists to assess patient insurance, eligibility, and accuracy of prescribed doses.
RESULTS: In the first year since service implementation in April 2016, 317 new prescriptions and 595 refill prescriptions were reviewed. A DOAC service pharmacist was able to reach 125 (39.4%) of 317 patients about their new prescription and 59 (9.9%) of 595 refill patients to provide education and follow-up on management as needed. Interventions were performed for 79 (28%) of 317 new prescriptions and 86 (14.5%) of 595 refill prescriptions. Common interventions with new prescriptions include contacting the prescriber for a medication or dose change (25.4%), assistance with medication access (21.5%), and coordinating appropriate lab and provider follow up (21.5%). Common interventions with refill prescriptions include recommending appropriate follow-up (50%) and contacting the prescriber for medication or dosage change (24.4%).
CONCLUSION: Implementation of a DOAC screening service identified and resolved dosing errors, improved medication access, provided patient education, and improved follow-up.

Entities:  

Keywords:  anticoagulation; apixaban; dabigatran; pharmacist; rivaroxaban

Mesh:

Substances:

Year:  2018        PMID: 30213217     DOI: 10.1177/0897190018799200

Source DB:  PubMed          Journal:  J Pharm Pract        ISSN: 0897-1900


  5 in total

1.  Therapeutic duplication of anticoagulants: a retrospective study of frequency and consequences in a tertiary referral hospital.

Authors:  Ramin Rahmanzade; Francisco Cabrera Diaz; Claudia Zaugg; Philipp Schuetz; Ali Reza Salili
Journal:  Thromb J       Date:  2020-08-03

2.  Optimization of DOAC management services in a centralized anticoagulation clinic.

Authors:  Katelyn W Sylvester; Alisia Chen; Andrea Lewin; John Fanikos; Samuel Z Goldhaber; Jean M Connors
Journal:  Res Pract Thromb Haemost       Date:  2022-05-05

3.  Evaluation of Direct Oral Anticoagulant Prescribing in Patients With Moderate to Severe Renal Impairment.

Authors:  Clara Ting; Megan Rhoten; Jillian Dempsey; Hunter Nichols; John Fanikos; Christian T Ruff
Journal:  Clin Appl Thromb Hemost       Date:  2021 Jan-Dec       Impact factor: 2.389

4.  Drug-related problem characterization and the solved status associated factor analysis in a pharmacist-managed anticoagulation clinic.

Authors:  Ju-Chieh Wung; Hsin-Chung Lin; Chia-Chen Hsu; Chia-Chieh Lin; Szu-Yu Wang; Shih-Lin Chang; Yuh-Lih Chang
Journal:  PLoS One       Date:  2022-08-15       Impact factor: 3.752

5.  Implementation of warfarin to direct oral anticoagulant conversion initiative in pharmacist-run anticoagulation clinics during COVID-19 pandemic.

Authors:  Katie Kish; Sanela Lekic
Journal:  J Am Coll Clin Pharm       Date:  2021-06-08
  5 in total

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