| Literature DB >> 3021287 |
K B Austin, J Bronzino, P J Morgane.
Abstract
Long-term potentiation (LTP) was studied in the dentate gyrus of anesthetized normal and prenatally protein malnourished rats in adulthood. LTP was initiated by high-frequency stimulation of the perforant path. Potentiation of both population excitatory postsynaptic potential (EPSP) slope and population spike was studied at various times after conditioning out to 5 h. The results indicate that prenatal protein malnutrition has a differential effect on LTP. Although potentiation of the population spike was relatively unaffected, prenatal protein malnutrition did lead to a significant reduction in potentiation of the population EPSP. Several possibilities are proposed as to the cause of the differential effect.Entities:
Mesh：
Year: 1986 PMID： 3021287 DOI： 10.1016/0165-3806(86)90102-1
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252