| Literature DB >> 3021230 |
R D pukoski, H V Sparks, L M Mela-Riker.
Abstract
Adenosine production by isolated rat heart mitochondria was examined and was observed to be dependent on an active adenine nucleotide transporter and a functional 5'-nucleotidase. It was found that mitochondria do not transport adenosine. These results suggest that mitochondria provide AMP for an extramitochondrial 5'-nucleotidase and this was verified by direct measurement of extramitochondrial levels of AMP and adenosine. A possible role for mitochondria in myocardial adenosine production is discussed.Entities:
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Year: 1986 PMID： 3021230 DOI： 10.1016/0304-4165(86)90222-9
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002