Literature DB >> 30210667

New advances in immunotherapy for non-small cell lung cancer.

Haifeng Qin1, Fang Wang1, Hui Liu1, Zhen Zeng1, Shasha Wang1, Xin Pan1, Hongjun Gao1.   

Abstract

Immunotherapy is one of the methods that can change the survival rate of patients with malignant tumors, in addition to surgery therapy, radiotherapy, chemotherapy and targeted therapy. Among various immunotherapy methods, immunoprecipitation inhibitors have been the most effective medications developed in recent years. At present, more in-depth studies have been conducted for two immune checkpoint inhibitor pathways, programmed cell death protein 1 (PD-1)/Programmed death-ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), and a variety of medications for those above mentioned. The present study briefly reviews the results of clinical trials for relevant immune checkpoint inhibitors in lung cancer.

Entities:  

Keywords:  CTLA-4; NSCLC; PD-1/PD-L1; biomarkers; immunotherapy

Year:  2018        PMID: 30210667      PMCID: PMC6129543     

Source DB:  PubMed          Journal:  Am J Transl Res            Impact factor:   4.060


  55 in total

1.  CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Authors:  Yu-Hwa Huang; Chen Zhu; Yasuyuki Kondo; Ana C Anderson; Amit Gandhi; Andrew Russell; Stephanie K Dougan; Britt-Sabina Petersen; Espen Melum; Thomas Pertel; Kiera L Clayton; Monika Raab; Qiang Chen; Nicole Beauchemin; Paul J Yazaki; Michal Pyzik; Mario A Ostrowski; Jonathan N Glickman; Christopher E Rudd; Hidde L Ploegh; Andre Franke; Gregory A Petsko; Vijay K Kuchroo; Richard S Blumberg
Journal:  Nature       Date:  2014-10-26       Impact factor: 49.962

2.  Molecular basis of T cell inactivation by CTLA-4.

Authors:  K M Lee; E Chuang; M Griffin; R Khattri; D K Hong; W Zhang; D Straus; L E Samelson; C B Thompson; J A Bluestone
Journal:  Science       Date:  1998-12-18       Impact factor: 47.728

3.  Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.

Authors:  Laurent Monney; Catherine A Sabatos; Jason L Gaglia; Akemi Ryu; Hanspeter Waldner; Tatyana Chernova; Stephen Manning; Edward A Greenfield; Anthony J Coyle; Raymond A Sobel; Gordon J Freeman; Vijay K Kuchroo
Journal:  Nature       Date:  2002-01-31       Impact factor: 49.962

4.  Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.

Authors:  Scott N Gettinger; Leora Horn; Leena Gandhi; David R Spigel; Scott J Antonia; Naiyer A Rizvi; John D Powderly; Rebecca S Heist; Richard D Carvajal; David M Jackman; Lecia V Sequist; David C Smith; Philip Leming; David P Carbone; Mary C Pinder-Schenck; Suzanne L Topalian; F Stephen Hodi; Jeffrey A Sosman; Mario Sznol; David F McDermott; Drew M Pardoll; Vindira Sankar; Christoph M Ahlers; Mark Salvati; Jon M Wigginton; Matthew D Hellmann; Georgia D Kollia; Ashok K Gupta; Julie R Brahmer
Journal:  J Clin Oncol       Date:  2015-04-20       Impact factor: 44.544

5.  Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.

Authors:  Roy S Herbst; Jean-Charles Soria; Marcin Kowanetz; Gregg D Fine; Omid Hamid; Michael S Gordon; Jeffery A Sosman; David F McDermott; John D Powderly; Scott N Gettinger; Holbrook E K Kohrt; Leora Horn; Donald P Lawrence; Sandra Rost; Maya Leabman; Yuanyuan Xiao; Ahmad Mokatrin; Hartmut Koeppen; Priti S Hegde; Ira Mellman; Daniel S Chen; F Stephen Hodi
Journal:  Nature       Date:  2014-11-27       Impact factor: 49.962

6.  Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study.

Authors:  Thomas J Lynch; Igor Bondarenko; Alexander Luft; Piotr Serwatowski; Fabrice Barlesi; Raju Chacko; Martin Sebastian; Joel Neal; Haolan Lu; Jean-Marie Cuillerot; Martin Reck
Journal:  J Clin Oncol       Date:  2012-04-30       Impact factor: 44.544

7.  Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.

Authors:  Suzanne L Topalian; F Stephen Hodi; Julie R Brahmer; Scott N Gettinger; David C Smith; David F McDermott; John D Powderly; Richard D Carvajal; Jeffrey A Sosman; Michael B Atkins; Philip D Leming; David R Spigel; Scott J Antonia; Leora Horn; Charles G Drake; Drew M Pardoll; Lieping Chen; William H Sharfman; Robert A Anders; Janis M Taube; Tracee L McMiller; Haiying Xu; Alan J Korman; Maria Jure-Kunkel; Shruti Agrawal; Daniel McDonald; Georgia D Kollia; Ashok Gupta; Jon M Wigginton; Mario Sznol
Journal:  N Engl J Med       Date:  2012-06-02       Impact factor: 91.245

8.  Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.

Authors:  Hossein Borghaei; Luis Paz-Ares; Leora Horn; David R Spigel; Martin Steins; Neal E Ready; Laura Q Chow; Everett E Vokes; Enriqueta Felip; Esther Holgado; Fabrice Barlesi; Martin Kohlhäufl; Oscar Arrieta; Marco Angelo Burgio; Jérôme Fayette; Hervé Lena; Elena Poddubskaya; David E Gerber; Scott N Gettinger; Charles M Rudin; Naiyer Rizvi; Lucio Crinò; George R Blumenschein; Scott J Antonia; Cécile Dorange; Christopher T Harbison; Friedrich Graf Finckenstein; Julie R Brahmer
Journal:  N Engl J Med       Date:  2015-09-27       Impact factor: 91.245

Review 9.  Immunotherapy for metastatic solid cancers.

Authors:  Simon Turcotte; Steven A Rosenberg
Journal:  Adv Surg       Date:  2011

10.  CTLA-4 ligation blocks CD28-dependent T cell activation.

Authors:  T L Walunas; C Y Bakker; J A Bluestone
Journal:  J Exp Med       Date:  1996-06-01       Impact factor: 14.307

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  18 in total

1.  Circular RNA EPB41 expression predicts unfavorable prognoses in NSCLC by regulating miR-486-3p/eIF5A axis-mediated stemness.

Authors:  Mingming Jin; Xiyu Liu; Yue Wu; Yuqing Lou; Xue Li; Gang Huang
Journal:  Cancer Cell Int       Date:  2022-06-20       Impact factor: 6.429

2.  Prognostic value of patient-reported outcome measures (PROMs) in adults with non-small cell Lung Cancer: a scoping review.

Authors:  Kuan Liao; Tianxiao Wang; Jake Coomber-Moore; David C Wong; Fabio Gomes; Corinne Faivre-Finn; Matthew Sperrin; Janelle Yorke; Sabine N van der Veer
Journal:  BMC Cancer       Date:  2022-10-19       Impact factor: 4.638

3.  An Episode of Pseudothrombocytopenia during Pembrolizumab Therapy in NSCLC Patient.

Authors:  Kinga Krukowska; Robert Kieszko; Katarzyna Kurek; Izabela Chmielewska; Paweł Krawczyk; Janusz Milanowski
Journal:  Case Rep Oncol Med       Date:  2020-05-08

Review 4.  Structure and Dynamics of the EGF Receptor as Revealed by Experiments and Simulations and Its Relevance to Non-Small Cell Lung Cancer.

Authors:  Marisa L Martin-Fernandez; David T Clarke; Selene K Roberts; Laura C Zanetti-Domingues; Francesco L Gervasio
Journal:  Cells       Date:  2019-04-05       Impact factor: 6.600

Review 5.  Immune checkpoint inhibitor treatment in patients with oncogene- addicted non-small cell lung cancer (NSCLC): summary of a multidisciplinary round-table discussion.

Authors:  Anna S Berghoff; Beatriz Bellosillo; Christophe Caux; Adrianus de Langen; Julien Mazieres; Nicola Normanno; Matthias Preusser; Mariano Provencio; Federico Rojo; Jurgen Wolf; Christoph C Zielinski
Journal:  ESMO Open       Date:  2019-06-17

6.  MiR-34c acts as a tumor suppressor in non-small cell lung cancer by inducing endoplasmic reticulum stress through targeting HMGB1.

Authors:  Li Tu; Ping Xu; Xiang Long; Weidong Song; Zhongdong Lv; Huadong Zeng; Tiezhu Wang; Xianglu Liu; Juanni Dong
Journal:  Onco Targets Ther       Date:  2019-07-16       Impact factor: 4.147

7.  Downregulation of hsa-microRNA-204-5p and identification of its potential regulatory network in non-small cell lung cancer: RT-qPCR, bioinformatic- and meta-analyses.

Authors:  Chang-Yu Liang; Zu-Yun Li; Ting-Qing Gan; Ye-Ying Fang; Bin-Liang Gan; Wen-Jie Chen; Yi-Wu Dang; Ke Shi; Zhen-Bo Feng; Gang Chen
Journal:  Respir Res       Date:  2020-02-26

8.  lncRNA ZEB2-AS1 Aggravates Progression of Non-Small Cell Lung Carcinoma via Suppressing PTEN Level.

Authors:  Xiao Chen; Kangwu Wang
Journal:  Med Sci Monit       Date:  2019-11-07

9.  Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC.

Authors:  Pierre-Olivier Gaudreau; Marcelo V Negrao; Kyle G Mitchell; Alexandre Reuben; Erin M Corsini; Jun Li; Tatiana V Karpinets; Qi Wang; Lixia Diao; Jing Wang; Lorenzo Federico; Edwin R Parra-Cuentas; Roohussaba Khairullah; Carmen Behrens; Arlene M Correa; Daniel Gomez; Latasha Little; Curtis Gumbs; Humam N Kadara; Junya Fujimoto; Daniel J McGrail; Ara A Vaporciyan; Stephen G Swisher; Garrett Walsh; Mara B Antonoff; Annikka Weissferdt; Hai Tran; Emily Roarty; Cara Haymaker; Chantale Bernatchez; Jianhua Zhang; P Andrew Futreal; Ignacio I Wistuba; Tina Cascone; John V Heymach; Boris Sepesi; Jianjun Zhang; Don L Gibbons
Journal:  J Thorac Oncol       Date:  2020-10-21       Impact factor: 15.609

Review 10.  Convex probe endobronchial ultrasound: historical, contemporary, and cutting-edge applications.

Authors:  Sameer K Avasarala; Carlos Aravena; Francisco A Almeida
Journal:  J Thorac Dis       Date:  2020-03       Impact factor: 3.005

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