| Literature DB >> 30210667 |
Haifeng Qin1, Fang Wang1, Hui Liu1, Zhen Zeng1, Shasha Wang1, Xin Pan1, Hongjun Gao1.
Abstract
Immunotherapy is one of the methods that can change the survival rate of patients with malignant tumors, in addition to surgery therapy, radiotherapy, chemotherapy and targeted therapy. Among various immunotherapy methods, immunoprecipitation inhibitors have been the most effective medications developed in recent years. At present, more in-depth studies have been conducted for two immune checkpoint inhibitor pathways, programmed cell death protein 1 (PD-1)/Programmed death-ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), and a variety of medications for those above mentioned. The present study briefly reviews the results of clinical trials for relevant immune checkpoint inhibitors in lung cancer.Entities:
Keywords: CTLA-4; NSCLC; PD-1/PD-L1; biomarkers; immunotherapy
Year: 2018 PMID: 30210667 PMCID: PMC6129543
Source DB: PubMed Journal: Am J Transl Res Impact factor: 4.060