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Literature DB >> 3021053

In vitro cytotoxicity and antibiotic activity of polymyxin B nonapeptide.

A K Duwe, C A Rupar, G B Horsman, S I Vas.

Abstract

Polymyxin B nonapeptide, prepared by enzymic removal of the fatty acyl diaminobutyric acid side chain from polymyxin B, was about 100-fold less toxic to K562 cells than polymyxin B. MICs of polymyxin B nonapeptide against a test panel of bacteria were 2- to 64-fold lower than those of polymyxin B.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1986 PMID： 3021053 PMCID： PMC180550 DOI： 10.1128/AAC.30.2.340

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

6 in total

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Journal: J Antibiot (Tokyo) Date: 1977-12 Impact factor: 2.649

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Authors: P Viljanen; M Vaara
Journal: Antimicrob Agents Chemother Date: 1984-06 Impact factor: 5.191

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Authors: M Vaara; P Viljanen
Journal: Antimicrob Agents Chemother Date: 1985-04 Impact factor: 5.191

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Authors: M Vaara; P Viljanen; T Vaara; P H Mäkelä
Journal: J Immunol Date: 1984-05 Impact factor: 5.422

6. Polycations as outer membrane-disorganizing agents.

Authors: M Vaara; T Vaara
Journal: Antimicrob Agents Chemother Date: 1983-07 Impact factor: 5.191

6 in total

18 in total

1. Determination of Residual Antibiotics in Cryopreserved Heart Valve Allografts.

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Journal: Transfus Med Hemother Date: 2011-11-14 Impact factor: 3.747

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Authors: M Vaara
Journal: Microbiol Rev Date: 1992-09

3. Isolation of a Paenibacillus sp. strain and structural elucidation of its broad-spectrum lipopeptide antibiotic.

Authors: Yaoqi Guo; En Huang; Chunhua Yuan; Liwen Zhang; Ahmed E Yousef
Journal: Appl Environ Microbiol Date: 2012-02-24 Impact factor: 4.792

4. Neopeptide antibiotics that function as opsonins and membrane-permeabilizing agents for gram-negative bacteria.

Authors: Haim Tsubery; Hertzig Yaakov; Sofia Cohen; Tal Giterman; Ariella Matityahou; Mati Fridkin; Itzhak Ofek
Journal: Antimicrob Agents Chemother Date: 2005-08 Impact factor: 5.191

5. Antibacterial synergism of polymyxin B nonapeptide and hydrophobic antibiotics in experimental gram-negative infections in mice.

Authors: I Ofek; S Cohen; R Rahmani; K Kabha; D Tamarkin; Y Herzig; E Rubinstein
Journal: Antimicrob Agents Chemother Date: 1994-02 Impact factor: 5.191

6. Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843.

Authors: Sathiah Thennarasu; Dong-Kuk Lee; Anmin Tan; U Prasad Kari; Ayyalusamy Ramamoorthy
Journal: Biochim Biophys Acta Date: 2005-03-07

7. Different surface charge of colistin-susceptible and -resistant Acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment.

Authors: Rachel L Soon; Roger L Nation; Stewart Cockram; Jennifer H Moffatt; Marina Harper; Ben Adler; John D Boyce; Ian Larson; Jian Li
Journal: J Antimicrob Chemother Date: 2010-11-16 Impact factor: 5.790