Literature DB >> 30209656

Generation of Human Neural Stem Cells by Direct Phenotypic Conversion.

Daekee Kwon1, Hee-Jin Ahn1, Kyung-Sun Kang2,3.   

Abstract

Human neural stem cells (hNSC) are multipotent adult stem cells. Various studies are underway worldwide to identify new methods for treatment of neurological diseases using hNSC. This chapter summarizes the latest research trends in and fields for application of patient-specific hNSC using direct phenotypic conversion technology. The aim of the study was to analyze the advantages and disadvantages of current technology and to suggest relevant directions for future hNSC research.

Entities:  

Keywords:  Cell replacement therapy; Direct phenotypic conversion; Disease modeling; Drug screening; Induced neural stem cells; Reprogramming

Mesh:

Year:  2018        PMID: 30209656     DOI: 10.1007/978-3-319-93485-3_4

Source DB:  PubMed          Journal:  Results Probl Cell Differ        ISSN: 0080-1844


  3 in total

1.  SOD3 overexpression alleviates cerebral ischemia-reperfusion injury in rats.

Authors:  Shuaiqi Sun; Ning Gao; Xiqi Hu; Han Luo; Jun Peng; Ying Xia
Journal:  Mol Genet Genomic Med       Date:  2019-08-28       Impact factor: 2.183

2.  Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann-Pick disease type C.

Authors:  Seung-Eun Lee; Nari Shin; Myung Geun Kook; Dasom Kong; Nam Gyo Kim; Soon Won Choi; Kyung-Sun Kang
Journal:  Cell Death Dis       Date:  2020-12-12       Impact factor: 8.469

3.  Vascularization of iNSC spheroid in a 3D spheroid-on-a-chip platform enhances neural maturation.

Authors:  Nari Shin; Youngtaek Kim; Jihoon Ko; Soon Won Choi; Sujin Hyung; Seung-Eun Lee; Seunghyuk Park; Jiyoung Song; Noo Li Jeon; Kyung-Sun Kang
Journal:  Biotechnol Bioeng       Date:  2021-11-06       Impact factor: 4.395

  3 in total

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