Literature DB >> 30208314

Dual Dopaminergic Regulation of Corticostriatal Plasticity by Cholinergic Interneurons and Indirect Pathway Medium Spiny Neurons.

Shana M Augustin1, Jessica H Chancey1, David M Lovinger2.   

Abstract

Endocannabinoid (eCB)-mediated long-term depression (LTD) requires dopamine (DA) D2 receptors (D2Rs) for eCB mobilization. The cellular locus of the D2Rs involved in LTD induction remains highly debated. We directly examined the role in LTD induction of D2Rs expressed by striatal cholinergic interneurons (Chls) and indirect pathway medium spiny neurons (iMSNs) using neuron-specific targeted deletion of D2Rs. Deletion of Chl-D2Rs (Chl-Drd2KO) impaired LTD induction in both subtypes of MSNs. LTD induction was restored in the Chl-Drd2KO mice by an M1-selective muscarinic acetylcholine receptor antagonist. In contrast, after the deletion of iMSN-D2Rs (iMSN-Drd2KO), LTD induction was intact in MSNs. Separate interrogation of direct pathway and iMSNs revealed a deficit in LTD induction only at synapses onto iMSNs that lack D2Rs. LTD induction in iMSNs was restored by D2R agonist application. Our findings suggest that Chl D2Rs strongly modulate LTD induction in MSNs, with iMSN-D2Rs having a weaker, iMSN-specific, modulatory effect. Published by Elsevier Inc.

Entities:  

Keywords:  D2 receptors; cholinergic interneurons; dMSNs; iMSNs; long-term depression

Mesh：

Substances：

Year:  2018        PMID： 30208314      PMCID： PMC6182771          DOI： 10.1016/j.celrep.2018.08.042

Source DB:  PubMed          Journal:  Cell Rep            Impact factor:   9.423


  50 in total

1.  Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons.

Authors:  Zhongfeng Wang; Li Kai; Michelle Day; Jennifer Ronesi; Henry H Yin; Jun Ding; Tatiana Tkatch; David M Lovinger; D James Surmeier
Journal:  Neuron       Date:  2006-05-04       Impact factor: 17.173

Review 2.  Acetylcholine-dopamine balance hypothesis in the striatum: an update.

Authors:  Toshihiko Aosaki; Masami Miura; Takeo Suzuki; Kinya Nishimura; Masao Masuda
Journal:  Geriatr Gerontol Int       Date:  2010-07       Impact factor: 2.730

3.  Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation.

Authors:  Christina M Gremel; Jessica H Chancey; Brady K Atwood; Guoxiang Luo; Rachael Neve; Charu Ramakrishnan; Karl Deisseroth; David M Lovinger; Rui M Costa
Journal:  Neuron       Date:  2016-05-26       Impact factor: 17.173

4.  Regional and postnatal heterogeneity of activity-dependent long-term changes in synaptic efficacy in the dorsal striatum.

Authors:  J G Partridge; K C Tang; D M Lovinger
Journal:  J Neurophysiol       Date:  2000-09       Impact factor: 2.714

5.  Dopamine modulates release from corticostriatal terminals.

Authors:  Nigel S Bamford; Siobhan Robinson; Richard D Palmiter; John A Joyce; Cynthia Moore; Charles K Meshul
Journal:  J Neurosci       Date:  2004-10-27       Impact factor: 6.167

6.  Postsynaptic endocannabinoid release is critical to long-term depression in the striatum.

Authors:  G L Gerdeman; J Ronesi; D M Lovinger
Journal:  Nat Neurosci       Date:  2002-05       Impact factor: 24.884

7.  Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling.

Authors:  Julia C Lemos; Danielle M Friend; Alanna R Kaplan; Jung Hoon Shin; Marcelo Rubinstein; Alexxai V Kravitz; Veronica A Alvarez
Journal:  Neuron       Date:  2016-05-18       Impact factor: 17.173

Review 8.  Multiple dopamine functions at different time courses.

Authors:  Wolfram Schultz
Journal:  Annu Rev Neurosci       Date:  2007       Impact factor: 12.449

9.  SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.

Authors:  Cristiano Nazzaro; Barbara Greco; Milica Cerovic; Paul Baxter; Tiziana Rubino; Massimo Trusel; Daniela Parolaro; Tatiana Tkatch; Fabio Benfenati; Paola Pedarzani; Raffaella Tonini
Journal:  Nat Neurosci       Date:  2012-01-08       Impact factor: 24.884

10.  An Improved BAC Transgenic Fluorescent Reporter Line for Sensitive and Specific Identification of Striatonigral Medium Spiny Neurons.

Authors:  Kristen K Ade; Yehong Wan; Meng Chen; Bernd Gloss; Nicole Calakos
Journal:  Front Syst Neurosci       Date:  2011-06-08
View more
  25 in total

1.  Complex Movement Control in a Rat Model of Parkinsonian Falls: Bidirectional Control by Striatal Cholinergic Interneurons.

Authors:  Cassandra Avila; Aaron Kucinski; Martin Sarter
Journal:  J Neurosci       Date:  2020-06-18       Impact factor: 6.167

Review 2.  Disentangling the diverse roles of dopamine D2 receptors in striatal function and behavior.

Authors:  Eduardo F Gallo
Journal:  Neurochem Int       Date:  2019-02-01       Impact factor: 3.921

3.  Astrocyte Signaling Gates Long-Term Depression at Corticostriatal Synapses of the Direct Pathway.

Authors:  Anna Cavaccini; Caitlin Durkee; Paulo Kofuji; Raffaella Tonini; Alfonso Araque
Journal:  J Neurosci       Date:  2020-06-15       Impact factor: 6.167

4.  Activation of Astrocytes in the Dorsomedial Striatum Facilitates Transition From Habitual to Goal-Directed Reward-Seeking Behavior.

Authors:  Seungwoo Kang; Sa-Ik Hong; Jeyeon Lee; Lee Peyton; Matthew Baker; Sun Choi; Hyunjung Kim; Su-Youne Chang; Doo-Sup Choi
Journal:  Biol Psychiatry       Date:  2020-05-06       Impact factor: 13.382

5.  Basal forebrain chemogenetic inhibition disrupts the superior complex movement control of goal-tracking rats.

Authors:  Aaron Kucinski; Youngsoo Kim; Martin Sarter
Journal:  Behav Neurosci       Date:  2019-02       Impact factor: 1.912

Review 6.  Emerging roles of striatal dopamine D2 receptors in motivated behaviour: Implications for psychiatric disorders.

Authors:  Pedro R Olivetti; Peter D Balsam; Eleanor H Simpson; Christoph Kellendonk
Journal:  Basic Clin Pharmacol Toxicol       Date:  2019-06-28       Impact factor: 4.080

7.  A spotlight on the elusive striatal cholinergic interneuron.

Authors:  Anna E Ingebretson; Julia C Lemos
Journal:  Science       Date:  2021-04-23       Impact factor: 47.728

8.  Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice.

Authors:  Ashley R Helseth; Ricardo Hernandez-Martinez; Victoria L Hall; Matthew L Oliver; Brandon D Turner; Zachary F Caffall; Joseph E Rittiner; Miranda K Shipman; Connor S King; Viviana Gradinaru; Charles Gerfen; Mauro Costa-Mattioli; Nicole Calakos
Journal:  Science       Date:  2021-04-23       Impact factor: 47.728

Review 9.  Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements.

Authors:  Martin Sarter; Cassandra Avila; Aaron Kucinski; Eryn Donovan
Journal:  Mov Disord       Date:  2021-02-22       Impact factor: 10.338

10.  Investigating the role of striatal dopamine receptor 2 in motor coordination and balance: Insights into the pathogenesis of DYT1 dystonia.

Authors:  Yuning Liu; Hong Xing; Fumiaki Yokoi; David E Vaillancourt; Yuqing Li
Journal:  Behav Brain Res       Date:  2021-01-18       Impact factor: 3.332
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.