Literature DB >> 30205192

Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options.

Janaina de Cássia Orlandi Sardi1, Diego Romário Silva1, Maria José Soares Mendes-Giannini2, Pedro Luiz Rosalen3.   

Abstract

Candida auris emerged as a pathogen resistant to multiple antifungal and has been associated with nosocomial outbreaks with high transmission capacity between hospitalized individuals. C. auris was first described in 2009, after being isolated from the external ear canal discharge of a patient in Japan. The difficulty in identification, incorrect use of antifungal drugs, and treatment failure are causes of high mortality. Since then, C. auris has been increasingly reported from East Asia to North America, with substantial fatalities and misidentification. This review aims at describing the epidemiology, virulence, risk factors, resistance, and therapeutic options in C. auris infections.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Candida auris; Resistance; Virulence factor

Mesh:

Substances:

Year:  2018        PMID: 30205192     DOI: 10.1016/j.micpath.2018.09.014

Source DB:  PubMed          Journal:  Microb Pathog        ISSN: 0882-4010            Impact factor:   3.738


  25 in total

Review 1.  Candida auris: a fungus with identity crisis.

Authors:  Taissa Vila; Ahmed S Sultan; Daniel Montelongo-Jauregui; Mary Ann Jabra-Rizk
Journal:  Pathog Dis       Date:  2020-06-01       Impact factor: 3.166

2.  Potent Synergistic Interactions between Lopinavir and Azole Antifungal Drugs against Emerging Multidrug-Resistant Candida auris.

Authors:  Hassan E Eldesouky; Ehab A Salama; Nadia A Lanman; Tony R Hazbun; Mohamed N Seleem
Journal:  Antimicrob Agents Chemother       Date:  2020-12-16       Impact factor: 5.191

3.  Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response.

Authors:  Edubiel A Alpizar-Sosa; Nur Raihana Binti Ithnin; Wenbin Wei; Andrew W Pountain; Stefan K Weidt; Anne M Donachie; Ryan Ritchie; Emily A Dickie; Richard J S Burchmore; Paul W Denny; Michael P Barrett
Journal:  PLoS Negl Trop Dis       Date:  2022-09-28

4.  Innate immune responses against the fungal pathogen Candida auris.

Authors:  Yuanyuan Wang; Yun Zou; Xiaoqing Chen; Hao Li; Zhe Yin; Baocai Zhang; Yongbin Xu; Yiquan Zhang; Rulin Zhang; Xinhua Huang; Wenhui Yang; Chaoyue Xu; Tong Jiang; Qinyu Tang; Zili Zhou; Ying Ji; Yingqi Liu; Lingfei Hu; Jia Zhou; Yao Zhou; Jingjun Zhao; Ningning Liu; Guanghua Huang; Haishuang Chang; Wenxia Fang; Changbin Chen; Dongsheng Zhou
Journal:  Nat Commun       Date:  2022-06-21       Impact factor: 17.694

5.  Evaluation of Synergistic Activity of Isavuconazole or Voriconazole plus Anidulafungin and the Occurrence and Genetic Characterization of Candida auris Detected in a Surveillance Program.

Authors:  Michael A Pfaller; Shawn A Messer; Lalitagauri M Deshpande; Paul R Rhomberg; Eric A Utt; Mariana Castanheira
Journal:  Antimicrob Agents Chemother       Date:  2021-03-18       Impact factor: 5.191

6.  Functional and Comparative Analysis of Centromeres Reveals Clade-Specific Genome Rearrangements in Candida auris and a Chromosome Number Change in Related Species.

Authors:  Aswathy Narayanan; Rakesh Netha Vadnala; Promit Ganguly; Pavitra Selvakumar; Shivaprakash M Rudramurthy; Rajendra Prasad; Arunaloke Chakrabarti; Rahul Siddharthan; Kaustuv Sanyal
Journal:  mBio       Date:  2021-05-11       Impact factor: 7.867

Review 7.  Candida auris and other phylogenetically related species - a mini-review of the literature.

Authors:  Cristina Nicoleta Ciurea; Anca Delia Mare; Irina-Bianca Kosovski; Felicia Toma; Camelia Vintilă; Adrian Man
Journal:  Germs       Date:  2021-09-29

8.  Pathogenicity Assessment of Colombian Strains of Candida auris in the Galleria mellonella Invertebrate Model.

Authors:  Silvia Katherine Carvajal; Maira Alvarado; Yuli M Rodríguez; Claudia M Parra-Giraldo; Carmen Varón; Soraya E Morales-López; José Y Rodríguez; Beatriz L Gómez; Patricia Escandón
Journal:  J Fungi (Basel)       Date:  2021-05-21

9.  Candida auris and endogenous panophthalmitis: clinical and histopathological features.

Authors:  Mark P Breazzano; Andrea A Tooley; Kyle J Godfrey; Codrin E Iacob; Nicolas A Yannuzzi; Harry W Flynn
Journal:  Am J Ophthalmol Case Rep       Date:  2020-05-11

Review 10.  Adhesins of Yeasts: Protein Structure and Interactions.

Authors:  Ronnie G Willaert
Journal:  J Fungi (Basel)       Date:  2018-10-27
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