Literature DB >> 30204453

Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides.

Marie El Arba1, Sara E Dibrell1, Frederick Meece1, Doug E Frantz1.   

Abstract

The synthesis of densely functionalized trisubstituted and tetrasubstituted furans via a novel Ru(II)-catalyzed intramolecular cyclization of vinyl diazoesters is reported. The synthetic utility of these furans is further demonstrated through a simple acid-mediated reaction to access highly substituted Δα,β-butenolides.

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Year:  2018        PMID: 30204453     DOI: 10.1021/acs.orglett.8b02554

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Mechanistic Divergence in the Hydrogenative Synthesis of Furans and Butenolides: Ruthenium Carbenes Formed by gem-Hydrogenation or through Carbophilic Activation of Alkynes.

Authors:  Sebastian Peil; Alois Fürstner
Journal:  Angew Chem Int Ed Engl       Date:  2019-11-06       Impact factor: 15.336

  1 in total

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