Literature DB >> 30203912

Organ distribution without geographic boundaries: A possible framework for organ allocation.

Jon J Snyder1,2, Nicholas Salkowski1, Andrew Wey1, Joshua Pyke1, Ajay K Israni1,2,3,4, Bertram L Kasiske1,2,3,4.   

Abstract

The Final Rule mandates that organ allocation not be based on the transplant candidate's place of residence or listing, except as required by sound medical judgment and best use of donated organs, to avoid wasting organs and futile transplants, and to promote access and efficiency. Current Organ Procurement and Transplantation Network (OPTN) policies use donation service areas and OPTN regions to distribute and allocate organs for transplant. These policies have recently been called into question as not meeting the requirements of the Final Rule. Therefore, we propose using borderless allocation scores that combine medical priority scores with geographic feasibility scores. Medical priority scores are currently used in OPTN allocation policy, for example, the model for end-stage liver disease and the lung allocation score. Geographic feasibility scores can be developed to account for the effects of ischemia due to travel times, donor characteristics that modify the feasibility of traveling due to organ outcomes, and the costs of shipping organs over long distances. A borderless distribution and allocation system could address the goals of equity and utility, while fulfilling the mandates of the Final Rule and providing optimal use of a scare resource. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.

Entities:  

Keywords:  Organ Procurement and Transplantation Network (OPTN); Scientific Registry for Transplant Recipients (SRTR); editorial/personal viewpoint; organ procurement and allocation

Year:  2018        PMID: 30203912     DOI: 10.1111/ajt.15115

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  12 in total

1.  Geographic disparities in liver supply/demand ratio within fixed-distance and fixed-population circles.

Authors:  Christine E Haugen; Tanveen Ishaque; Abel Sapirstein; Alexander Cauneac; Dorry L Segev; Sommer Gentry
Journal:  Am J Transplant       Date:  2019-03-18       Impact factor: 8.086

2.  Perspectives on donor lung allocation from both sides of the Atlantic: The United States.

Authors:  Wayne M Tsuang; Laurie D Snyder; Marie M Budev
Journal:  Clin Transplant       Date:  2020-05-06       Impact factor: 2.863

3.  The Broader Sharing of Deceased Donor Kidneys Is an Ethical and Legal Imperative.

Authors:  Sharon E Klarman; Richard N Formica
Journal:  J Am Soc Nephrol       Date:  2020-04-20       Impact factor: 10.121

4.  Major Variation across Local Transplant Centers in Probability of Kidney Transplant for Wait-Listed Patients.

Authors:  Kristen L King; S Ali Husain; Jesse D Schold; Rachel E Patzer; Peter P Reese; Zhezhen Jin; Lloyd E Ratner; David J Cohen; Stephen O Pastan; Sumit Mohan
Journal:  J Am Soc Nephrol       Date:  2020-10-09       Impact factor: 10.121

5.  Quantifying Sex-Based Disparities in Liver Allocation.

Authors:  Jayme E Locke; Brittany A Shelton; Kim M Olthoff; Elizabeth A Pomfret; Kimberly A Forde; Deirdre Sawinski; Meagan Gray; Nancy L Ascher
Journal:  JAMA Surg       Date:  2020-07-15       Impact factor: 14.766

Review 6.  12 Plagues of AI in Healthcare: A Practical Guide to Current Issues With Using Machine Learning in a Medical Context.

Authors:  Stephane Doyen; Nicholas B Dadario
Journal:  Front Digit Health       Date:  2022-05-03

7.  New Kidney and Pancreas Allocation Policy: Moving to a Circle as the First Unit of Allocation.

Authors:  Ajay Israni; Andrew Wey; Bryn Thompson; Jon Miller; Vincent Casingal; Martha Pavlakis; Silke Niederhaus; Rachel Forbes; Amber Wilk; Warren McKinney; Raja Kandaswamy; Peter Stock; Jon Snyder
Journal:  J Am Soc Nephrol       Date:  2021-06-17       Impact factor: 14.978

8.  A Survey of Current Procurement Travel Practices, Accident Frequency, and Perceptions of Safety.

Authors:  Austin D Schenk; William K Washburn; Andrew B Adams; Raymond J Lynch
Journal:  Transplant Direct       Date:  2019-09-27

9.  A revealed preference analysis to develop composite scores approximating lung allocation policy in the U.S.

Authors:  Darren E Stewart; Dallas W Wood; James B Alcorn; Erika D Lease; Michael Hayes; Brett Hauber; Rebecca E Goff
Journal:  BMC Med Inform Decis Mak       Date:  2021-01-06       Impact factor: 2.796

10.  Geographic Variation in the Availability of Deceased Donor Kidneys per Wait-Listed Candidate in the United States.

Authors:  Kristen L King; S Ali Husain; Sumit Mohan
Journal:  Kidney Int Rep       Date:  2019-09-03
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