Literature DB >> 30202933

Primary Syphilis in the Male Urethra: A Case Report.

Laura C Chambers1, Sujatha Srinivasan2, Sheila A Lukehart3,4, Negusse Ocbamichael5, Jennifer L Morgan5, M Sylvan Lowens5, David N Fredricks2,3, Matthew R Golden3,5, Lisa E Manhart1.   

Abstract

We documented urethral Treponema pallidum infection in a man with nongonococcal urethritis and a negative syphilis serology using broad-range bacterial polymerase chain reaction (PCR) and sequencing, targeted PCR, and immunofluorescence microscopy. He subsequently seroconverted for syphilis. Early syphilis may present as urethritis. Urethral T. pallidum shedding can occur before seroconversion.
© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  zzm321990 Treponema pallidumzzm321990 ; 16S rRNA gene PCR; nongonococcal urethritis; primary syphilis

Mesh:

Year:  2019        PMID: 30202933      PMCID: PMC6424071          DOI: 10.1093/cid/ciy771

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  10 in total

1.  Macrolide resistance in Treponema pallidum in the United States and Ireland.

Authors:  Sheila A Lukehart; Charmie Godornes; Barbara J Molini; Patricia Sonnett; Susan Hopkins; Fiona Mulcahy; Joseph Engelman; Samuel J Mitchell; Anne M Rompalo; Christina M Marra; Jeffrey D Klausner
Journal:  N Engl J Med       Date:  2004-07-08       Impact factor: 91.245

2.  Evaluation of specific antibodies for early diagnosis and management of syphilis.

Authors:  Qianli Dang; Jie Feng; Xuedang Lu; Xiaoyan Zhang; Hanqing Xu; Chao Liu; Xinwu Nu
Journal:  Int J Dermatol       Date:  2006-10       Impact factor: 2.736

3.  Demonstration of Treponema pallidum in a cutaneous gumma by indirect immunofluorescence.

Authors:  H H Handsfield; S A Lukehart; S Sell; S J Norris; K K Holmes
Journal:  Arch Dermatol       Date:  1983-08

4.  Unexpectedly high prevalence of Treponema pallidum infection in the oral cavity of human immunodeficiency virus-infected patients with early syphilis who had engaged in unprotected sex practices.

Authors:  C-J Yang; S-Y Chang; B-R Wu; S-P Yang; W-C Liu; P-Y Wu; J-Y Zhang; Y-Z Luo; C-C Hung; S-C Chang
Journal:  Clin Microbiol Infect       Date:  2015-05-08       Impact factor: 8.067

Review 5.  Laboratory diagnosis and interpretation of tests for syphilis.

Authors:  S A Larsen; B M Steiner; A H Rudolph
Journal:  Clin Microbiol Rev       Date:  1995-01       Impact factor: 26.132

6.  Treatment and outcomes of polymerase chain reaction-confirmed early syphilis.

Authors:  Phillip J Read; Rebecca Guy; Neisha Jeoffreys; David Baker; Matthew Shields; Basil Donovan
Journal:  Sex Health       Date:  2015-11       Impact factor: 2.706

7.  Primary and secondary syphilis, 20 years' experience. 2. Clinical features.

Authors:  A Mindel; S J Tovey; D J Timmins; P Williams
Journal:  Genitourin Med       Date:  1989-01

8.  Development of a Multilocus Sequence Typing (MLST) scheme for Treponema pallidum subsp. pertenue: Application to yaws in Lihir Island, Papua New Guinea.

Authors:  Charmie Godornes; Lorenzo Giacani; Alyssa E Barry; Oriol Mitja; Sheila A Lukehart
Journal:  PLoS Negl Trop Dis       Date:  2017-12-27

9.  State-Specific Rates of Primary and Secondary Syphilis Among Men Who Have Sex with Men - United States, 2015.

Authors:  Alex de Voux; Sarah Kidd; Jeremy A Grey; Eli S Rosenberg; Thomas L Gift; Hillard Weinstock; Kyle T Bernstein
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2017-04-07       Impact factor: 17.586

10.  Stool Microbiota at Neutrophil Recovery Is Predictive for Severe Acute Graft vs Host Disease After Hematopoietic Cell Transplantation.

Authors:  Jonathan L Golob; Steven A Pergam; Sujatha Srinivasan; Tina L Fiedler; Congzhou Liu; Kristina Garcia; Marco Mielcarek; Daisy Ko; Sarah Aker; Sara Marquis; Tillie Loeffelholz; Anna Plantinga; Michael C Wu; Kevin Celustka; Alex Morrison; Maresa Woodfield; David N Fredricks
Journal:  Clin Infect Dis       Date:  2017-11-29       Impact factor: 9.079

  10 in total
  3 in total

1.  What Is the Evidence for the Sexual Transmission of Syphilis From Asymptomatic Persons?

Authors:  Susan Tuddenham; Khalil G Ghanem
Journal:  Sex Transm Dis       Date:  2019-06       Impact factor: 2.830

2.  Treponema pallidum Nucleic Acid Amplification Testing To Augment Syphilis Screening among Men Who Have Sex with Men.

Authors:  Matthew Golden; Meghan O'Donnell; Sheila Lukehart; Paul Swenson; Paul Hovey; Charmie Godornes; Sarah Romano; Damon Getman
Journal:  J Clin Microbiol       Date:  2019-07-26       Impact factor: 5.948

3.  Analytical Performance Characteristics of a New Transcription-Mediated Amplification Assay for Treponema pallidum.

Authors:  Damon Getman; Mike Lin; Nesreen Barakat; Rhonda Skvoretz; Charmie Godornes; Paul Swenson; Ashley Nenninger; Matthew R Golden; Sheila A Lukehart
Journal:  J Clin Microbiol       Date:  2021-07-19       Impact factor: 5.948

  3 in total

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