| Literature DB >> 30202933 |
Laura C Chambers1, Sujatha Srinivasan2, Sheila A Lukehart3,4, Negusse Ocbamichael5, Jennifer L Morgan5, M Sylvan Lowens5, David N Fredricks2,3, Matthew R Golden3,5, Lisa E Manhart1.
Abstract
We documented urethral Treponema pallidum infection in a man with nongonococcal urethritis and a negative syphilis serology using broad-range bacterial polymerase chain reaction (PCR) and sequencing, targeted PCR, and immunofluorescence microscopy. He subsequently seroconverted for syphilis. Early syphilis may present as urethritis. Urethral T. pallidum shedding can occur before seroconversion.Entities:
Keywords: zzm321990 Treponema pallidumzzm321990 ; 16S rRNA gene PCR; nongonococcal urethritis; primary syphilis
Mesh:
Year: 2019 PMID: 30202933 PMCID: PMC6424071 DOI: 10.1093/cid/ciy771
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079