Immune Function: Impact of Exercise and Nutritional Interventions.

This article provides a brief commentary on the accompanying article, "Nutrition and Physical Activity Interventions to Improve Immunity" by Davison, Kehaya, and Jones. The article reviews the evidence on physical exercise and/or nutrition in modulating immune response, with a specific focus on the prevention of respiratory infection. Given the large scope of the review, an overview of current findings is presented, rather than in-depth discussions, and the nutritional strategies discussed tend to focus on the strategies that have been studied in the context of exercise. Some further insight is provided in the commentary on potential mechanisms that may explain the benefits of exercise, a brief discussion on the impact of obesity and host defense, and future directions for research. In general, the article sufficiently describes the current evidence, and draws appropriate conclusions based on the evidence presented. The article is recommended for audiences that have limited background on these topics, and for those who are familiar with this line of research.