Literature DB >> 30202255

Potentially Driver-Impairing Medications: Risks and Strategies for Injury Prevention.

Timothy Ivers1, Nicole D White1.   

Abstract

Impaired driving is a major cause of motor vehicle accidents, injury, and fatality. Several classes of medication have been found to affect a driver's cognition, judgment, and reaction time and may put patients at increased risk for accidents and injury. This article will explore medications with side effects posing a potential threat to drivers, including anxiolytics, sedative hypnotics, antihistamines, and antidepressants, as well as describe potential strategies for mitigating or minimizing such risks.

Entities:  

Keywords:  antidepressants; antihistamines; benzodiazepines; driver impairment; motor vehicle accidents; sedative hypnotics

Year:  2016        PMID: 30202255      PMCID: PMC6124861          DOI: 10.1177/1559827615609050

Source DB:  PubMed          Journal:  Am J Lifestyle Med        ISSN: 1559-8276


  13 in total

Review 1.  Antidepressants and driver impairment: empirical evidence from a standard on-the-road test.

Authors:  Johannes G Ramaekers
Journal:  J Clin Psychiatry       Date:  2003-01       Impact factor: 4.384

2.  Benzodiazepine use and the risk of motor vehicle crash in the elderly.

Authors:  B Hemmelgarn; S Suissa; A Huang; J F Boivin; G Pinard
Journal:  JAMA       Date:  1997-07-02       Impact factor: 56.272

3.  Sedative Hypnotic Medication Use and the Risk of Motor Vehicle Crash.

Authors:  Ryan N Hansen; Denise M Boudreau; Beth E Ebel; David C Grossman; Sean D Sullivan
Journal:  Am J Public Health       Date:  2015-06-11       Impact factor: 9.308

Review 4.  Middle-of-the-night administration of sleep medication: a critical review of the effects on next morning driving ability.

Authors:  Joris C Verster; Aurora J A E van de Loo; Margaret L Moline; Thomas Roth
Journal:  Curr Drug Saf       Date:  2014

Review 5.  The relationship between benzodiazepine use and traffic accidents: A systematic literature review.

Authors:  Beitske E Smink; Antoine C G Egberts; Klaas J Lusthof; Donald R A Uges; Johan J de Gier
Journal:  CNS Drugs       Date:  2010-08       Impact factor: 5.749

6.  Driving under the influence of drugs in Sweden with zero concentration limits in blood for controlled substances.

Authors:  Alan Wayne Jones
Journal:  Traffic Inj Prev       Date:  2005-12       Impact factor: 1.491

Review 7.  Effects of benzodiazepines, antidepressants and opioids on driving: a systematic review and meta-analysis of epidemiological and experimental evidence.

Authors:  Tharaka Dassanayake; Patricia Michie; Gregory Carter; Alison Jones
Journal:  Drug Saf       Date:  2011-02-01       Impact factor: 5.606

8.  Acute and subchronic effects of nefazodone and imipramine on highway driving, cognitive functions, and daytime sleepiness in healthy adult and elderly subjects.

Authors:  M W van Laar; A P van Willigenburg; E R Volkerts
Journal:  J Clin Psychopharmacol       Date:  1995-02       Impact factor: 3.153

9.  Venlafaxine's effects on healthy volunteers' driving, psychomotor, and vigilance performance during 15-day fixed and incremental dosing regimens.

Authors:  J F O'Hanlon; H W Robbe; A Vermeeren; C van Leeuwen; P E Danjou
Journal:  J Clin Psychopharmacol       Date:  1998-06       Impact factor: 3.153

10.  The impact of benzodiazepines on safe driving.

Authors:  Sacha Dubois; Michel Bédard; Bruce Weaver
Journal:  Traffic Inj Prev       Date:  2008-10       Impact factor: 1.491

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  2 in total

1.  Examining Patterns of Driving Avoidance Behaviors Among Older People Using Latent Class Analysis.

Authors:  Laurie F Beck; Feijun Luo; Bethany A West
Journal:  J Appl Gerontol       Date:  2022-04-20

2.  Increased variability in reaction time is associated with amyloid beta pathology at age 70.

Authors:  Kirsty Lu; Jennifer M Nicholas; Sarah-Naomi James; Christopher A Lane; Thomas D Parker; Ashvini Keshavan; Sarah E Keuss; Sarah M Buchanan; Heidi Murray-Smith; David M Cash; Carole H Sudre; Ian B Malone; William Coath; Andrew Wong; Susie M D Henley; Nick C Fox; Marcus Richards; Jonathan M Schott; Sebastian J Crutch
Journal:  Alzheimers Dement (Amst)       Date:  2020-08-10
  2 in total

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