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Literature DB >> 3019890

Copurification of Leptospira interrogans serovar pomona hemolysin and sphingomyelinase C.

Abstract

The hemolytic and sphingomyelinase C activities of supernatants of cultures of Leptospira interrogans serovar pomona tended to copurify when isoelectric fractionation was carried out. Both activities focused primarily at pH 8.1. Considered in conjunction with other circumstantial evidence, the results led to the conclusion that sphingomyelinase C is responsible for hemolysis.

Entities: Disease Species

Mesh：

Substances：

Year: 1986 PMID： 3019890 PMCID： PMC260148 DOI： 10.1128/iai.54.1.262-264.1986

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

19 in total

1. Properties of a toxin from the sea anemone Stoichacis helianthus, including specific binding to sphingomyelin.

Authors: A W Bernheimer; L S Avigad
Journal: Proc Natl Acad Sci U S A Date: 1976-02 Impact factor: 11.205

2. A hemolysin associated with leptospirae.

Authors: C M RUSSELL
Journal: J Immunol Date: 1956-12 Impact factor: 5.422

3. Presence of hemolysin in cultures of pathogenic leptospires.

Authors: A D ALEXANDER; O H SMITH; C W HIATT; C A GLEISER
Journal: Proc Soc Exp Biol Med Date: 1956-02

4. [Sphingomyelinase activity of Leptospira cultures (author's transl)].

Authors: S Bazovská
Journal: Cesk Epidemiol Mikrobiol Imunol Date: 1978-06

Review 5. Nonenteric toxins of Staphylococcus aureus.

Authors: M Rogolsky
Journal: Microbiol Rev Date: 1979-09

6. Immunogenicity of whole cell and outer envelope leptospiral vaccines in hamsters.

Authors: R F Bey; N E Auran; R C Johnson
Journal: Infect Immun Date: 1974-11 Impact factor: 3.441

7. Staphylococcal sphingomyelinase (beta-hemolysin).

Authors: A W Bernheimer; L S Avigad; K S Kim
Journal: Ann N Y Acad Sci Date: 1974-07-31 Impact factor: 5.691

8. A practical chromogenic procedure for the detection of homozygotes and heterozygous carriers of Niemann-Pick disease.

Authors: A E Gal; R O Brady; S R Hibbert; P G Pentchev
Journal: N Engl J Med Date: 1975-09-25 Impact factor: 91.245

9. Studies on extracellular PROTEINS FROM Staphylococcus aureus. I. Separation and characterization of enzymes and toxins by isoelectric focusing.

Authors: O Vesterberg; T Wadström; K Vesterberg; H Svensson; B Malmgren
Journal: Biochim Biophys Acta Date: 1967-04-11

10. Characterization of inhibitor to leptospiral hemolysin present in bovine serum.

Authors: T Kojima; Y Yanagihara; I Mifuchi
Journal: Microbiol Immunol Date: 1984 Impact factor: 1.955

17 in total

Review 1. Leptospirosis.

Authors: P N Levett
Journal: Clin Microbiol Rev Date: 2001-04 Impact factor: 26.132

Copurification of Leptospira interrogans serovar pomona hemolysin and sphingomyelinase C.

1. Properties of a toxin from the sea anemone Stoichacis helianthus, including specific binding to sphingomyelin.

2. A hemolysin associated with leptospirae.

3. Presence of hemolysin in cultures of pathogenic leptospires.

4. [Sphingomyelinase activity of Leptospira cultures (author's transl)].

Review 5. Nonenteric toxins of Staphylococcus aureus.

6. Immunogenicity of whole cell and outer envelope leptospiral vaccines in hamsters.

7. Staphylococcal sphingomyelinase (beta-hemolysin).

8. A practical chromogenic procedure for the detection of homozygotes and heterozygous carriers of Niemann-Pick disease.

9. Studies on extracellular PROTEINS FROM Staphylococcus aureus. I. Separation and characterization of enzymes and toxins by isoelectric focusing.

10. Characterization of inhibitor to leptospiral hemolysin present in bovine serum.

Review 1. Leptospirosis.

2. Identification and partial characterization of a cytolytic toxin produced by Gardnerella vaginalis.

Review 3. Leptospira as an emerging pathogen: a review of its biology, pathogenesis and host immune responses.

4. Purification and characterization of a Na+, K+ ATPase inhibitor found in an endotoxin of Leptospira interrogans.

Review 5. Multiple leptospiral sphingomyelinases (or are there?).

Review 6. Potential role of phospholipases in virulence and fungal pathogenesis.

7. Cloning of a hemolysin gene from Leptospira interrogans serovar hardjo.

8. Cytotoxic activities of Leptospira interrogans hemolysin SphH as a pore-forming protein on mammalian cells.

9. Presence of putative sphingomyelinase genes among members of the family Leptospiraceae.

10. Novel observation of hot-cold-hot hemolysis exhibited by group B streptococci.