Yaser Ghavami1, Yarah M Haidar1, Omid Moshtaghi1, Harrison W Lin1, Hamid R Djalilian1,2. 1. 1 Division of Otology, Neurotology, and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, Irvine, CA, USA. 2. 2 Department of Biomedical Engineering, University of California, Irvine, Irvine, CA, USA.
Abstract
OBJECTIVE: : To evaluate the change in quality of life (QOL) of patients with Meniere's disease (MD) after treatment with migraine prophylaxis therapy. METHODS: : Patients with definite MD were given the Meniere's Disease Outcomes Questionnaire-Retrospective (MDOQ-R) after migraine prophylactic therapy to assess QOL. Changes in physical, emotional, and social parameters affected by MD were calculated, along with a global pre- and posttreatment QOL scores. RESULTS: : The MDOQ-R was given to 27 consecutive patients with definite MD. Patients who had at least an 18-month follow-up were included, resulting in 25 questionnaires. The mean change in QOL score was 25 ± 16 (range, -3 to 55), P = .02. Quality of life was improved in 23 (92%) of the respondents in every metric measured, unchanged in 1 (4%), and poorer in 1 (4%) of patients after migraine prophylaxis treatment. CONCLUSIONS: : Majority of MD patients who had all failed diuretic therapy responded positively to medications used for migraine prophylaxis, as indicated by a significant improvement in QOL. This study may further suggest a correlation between the pathophysiologic basis of disease in MD and vestibular migraine. Patients with MD may be successfully managed with medications intended to treat migraine.
OBJECTIVE: : To evaluate the change in quality of life (QOL) of patients with Meniere's disease (MD) after treatment with migraine prophylaxis therapy. METHODS: : Patients with definite MD were given the Meniere's Disease Outcomes Questionnaire-Retrospective (MDOQ-R) after migraine prophylactic therapy to assess QOL. Changes in physical, emotional, and social parameters affected by MD were calculated, along with a global pre- and posttreatment QOL scores. RESULTS: : The MDOQ-R was given to 27 consecutive patients with definite MD. Patients who had at least an 18-month follow-up were included, resulting in 25 questionnaires. The mean change in QOL score was 25 ± 16 (range, -3 to 55), P = .02. Quality of life was improved in 23 (92%) of the respondents in every metric measured, unchanged in 1 (4%), and poorer in 1 (4%) of patients after migraine prophylaxis treatment. CONCLUSIONS: : Majority of MD patients who had all failed diuretic therapy responded positively to medications used for migraine prophylaxis, as indicated by a significant improvement in QOL. This study may further suggest a correlation between the pathophysiologic basis of disease in MD and vestibular migraine. Patients with MD may be successfully managed with medications intended to treat migraine.
Authors: Vincent M Desiato; Jaimin J Patel; Shaun A Nguyen; Ted A Meyer; Paul R Lambert Journal: World J Otorhinolaryngol Head Neck Surg Date: 2020-04-23
Authors: Mehdi Abouzari; Khodayar Goshtasbi; Janice T Chua; Donald Tan; Brooke Sarna; Tina Saber; Harrison W Lin; Hamid R Djalilian Journal: Laryngoscope Date: 2020-04-03 Impact factor: 3.325
Authors: Mehdi Abouzari; Donald Tan; Brooke Sarna; Yaser Ghavami; Khodayar Goshtasbi; Erica M Parker; Harrison W Lin; Hamid R Djalilian Journal: Ann Otol Rhinol Laryngol Date: 2019-12-01 Impact factor: 1.547